Docosahexaenoic acid-d5
Based on 1 Customer Validation
Docosahexaenoic acid-d5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
For research use only. We do not sell to patients.
- Purity : 99.9%
- CAS No.: 1197205-71-2
- Formula: C22H27D5O2
- Molecular Weight:333.52
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Storage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-B2167
Docosahexaenoic acidomega-3 Fatty Acid -
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Eicosapentaenoic Acid-d5Stable Isotope -
HY-N1446S
Oleic acid-13CStable Isotope -
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4-Hydroxynonenal alkyneAzide -
HY-101988S
Prostaglandin D2-d4Stable Isotope -
HY-B0257S1
Norgestrel-d6Stable Isotope -
HY-W814363
Octadec-9-enoic acid-13C5Stable Isotope -
HY-B0141S
Estradiol-d3Stable Isotope -
HY-N0729S2
Linoleic acid-13C18Stable Isotope -
HY-N0523S
Gallic acid-d2Stable Isotope
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1197205-71-2
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Unlabeled CAS 6217-54-5
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Appearance Liquid
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Molecular Weight 333.52
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Formula C22H27D5O2
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Color Colorless to light yellow
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SMILES
[2H]C([2H])(C([2H])(/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O)[2H])[2H]
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Synonyms
DHA-d5; Cervonic acid-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Protocols
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Protocol for Fluorescence In Situ Hybridization (FISH)
Fluorescence in situ hybridization detects specific DNA or RNA sequences inside fixed cells or tissue sections by hybridizing fluorescently labeled nucleic-acid probes to complementary target sequences, allowing the target’s copy number, chromosomal position, spatial distribution, or transcript abundance to be visualized microscopically. DNA-FISH detects genomic loci, chromosomal gains/losses, amplifications, deletions, and rearrangements, while RNA-FISH detects RNA molecules or transcript localization; in cancer cells, mouse tumors, neurons, organoids, macrophages, or drug-screening samples, the readout is fluorescent puncta, fusion/split signals, or localized RNA signal interpreted relative to validated controls.
Purity & Documentation
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Data Sheet (262 KB)
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SDS (545 KB)
- English - EN (545 KB)
- Français - FR (545 KB)
- Deutsch - DE (545 KB)
- Norwegian - NO (545 KB)
- Español - ES (545 KB)
- Swedish - SV (545 KB)
- Italian - IT (545 KB)
- Korean - KR (545 KB)
- Portuguese - PT (545 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Horrocks LA, et al. Health benefits of docosahexaenoic acid (DHA). Pharmacol Res. 1999 Sep;40(3):211-25. [Content Brief]
[3]. Gharami K, et al. Essential role of docosahexaenoic acid towards development of a smarter brain. Neurochem Int. 2015 Oct;89:51-62. [Content Brief]
[4]. Lengqvist J, et al. Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid Xreceptor alpha ligand-binding domain. Mol Cell Proteomics. 2004 Jul;3(7):692-703. [Content Brief]
[5]. Gamoh S, et al. Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats. Neuroscience. 1999;93(1):237-41. [Content Brief]
[6]. Ozsoy O, et al. The influence and the mechanism of docosahexaenoic acid on a mouse model of Parkinson's disease. Neurochem Int. 2011 Oct;59(5):664-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Docosahexaenoic acid-d5 Related Classifications
HY-B2167S Related Classifications
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