2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Vanillylmandelic acid-d3

Vanillylmandelic acid-d3 is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM[1].

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Vanillylmandelic acid-d<sub>3</sub> Chemical Structure

Vanillylmandelic acid-d3 Chemical Structure

CAS No. : 74495-70-8

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Based on 1 publication(s) in Google Scholar

Other Forms of Vanillylmandelic acid-d3:

Vanillylmandelic acid-d3 Related Antibodies

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Description

Vanillylmandelic acid-d3 is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Vanillylmandelic acid-d3 Related Antibodies
Molecular Weight

201.19

Formula

C9H7D3O5
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

OC(C(C1=CC(OC([2H])([2H])[2H])=C(C=C1)O)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (621.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9704 mL 24.8521 mL 49.7043 mL
5 mM 0.9941 mL 4.9704 mL 9.9409 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.9704 mL 24.8521 mL 49.7043 mL 124.2606 mL
5 mM 0.9941 mL 4.9704 mL 9.9409 mL 24.8521 mL
10 mM 0.4970 mL 2.4852 mL 4.9704 mL 12.4261 mL
15 mM 0.3314 mL 1.6568 mL 3.3136 mL 8.2840 mL
20 mM 0.2485 mL 1.2426 mL 2.4852 mL 6.2130 mL
25 mM 0.1988 mL 0.9941 mL 1.9882 mL 4.9704 mL
30 mM 0.1657 mL 0.8284 mL 1.6568 mL 4.1420 mL
40 mM 0.1243 mL 0.6213 mL 1.2426 mL 3.1065 mL
50 mM 0.0994 mL 0.4970 mL 0.9941 mL 2.4852 mL
60 mM 0.0828 mL 0.4142 mL 0.8284 mL 2.0710 mL
80 mM 0.0621 mL 0.3107 mL 0.6213 mL 1.5533 mL
100 mM 0.0497 mL 0.2485 mL 0.4970 mL 1.2426 mL
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Vanillylmandelic acid-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vanillylmandelic acid-d374495-70-8Endogenous MetaboliteInhibitorinhibitorinhibit

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