55-10-7
55-10-7
Chemical Structure
Vanillylmandelic acid
- CAS No.: 55-10-7
- Formula:C9H10O5
- Molecular Weight:198.17
IUPAC Name: 2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetic acid
InChIKey: CGQCWMIAEPEHNQ-UHFFFAOYSA-N
SMILES: O=C(O)C(O)C1=CC=C(O)C(OC)=C1
Biological Activity: Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Vanillylmandelic acid | 99.78% | Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM. | ||||||||||||||||||||
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Vanillylmandelic acid (Standard) | 99.62% | Vanillylmandelic acid (Standard) is the analytical standard of Vanillylmandelic acid. This product is intended for research and analytical applications. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM. | ||||||||||||||||||||
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Vanillylmandelic acid-d | Vanillylmandelic acid-d is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM. | |||||||||||||||||||||
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Vanillylmandelic acid-d3 | 99.91% | Vanillylmandelic acid-d3 is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM. | ||||||||||||||||||||
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Vanillactic acid | 98.19% | Vanillactic acid (VLA) is a relevant biomarker associated with Aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency is a primary neurotransmitter defect of the biosynthesis of catecholamines and serotonin. | ||||||||||||||||||||
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3-Methoxy-4-hydroxyphenylglycol | 97.85% | 3-Methoxy-4-hydroxyphenylglycol (HMPG) is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol is an indicators of central nervous system noradrenergic activity. 3-Methoxy-4-hydroxyphenylglycol can be used for research of depression, chronic schizophrenia, etc. | ||||||||||||||||||||
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3-Methoxy-4-hydroxyphenylglycol-d3 | 99.50% | 3-Methoxy-4-hydroxyphenylglycol-d3 (HMPG-d3) is the deuterium labeled 3-Methoxy-4-hydroxyphenylglycol. 3-Methoxy-4-hydroxyphenylglycol is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol (HMPG) serves as an indicator of noradrenergic activity in the central nervous system. 3-Methoxy-4-hydroxyphenylglycol (HMPG) can be used for research on diseases such as depression and chronic schizophrenia. | ||||||||||||||||||||
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3-O-Methyldopa-d3 | 99.9% | 3-O-Methyldopa-d3 (3-Methoxy-L-tyrosine-d3) is deuterium labeled 3-O-Methyldopa (HY-113468A). 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA (HY-N0304) that can cross the blood-brain barrier (BBB). 3-O-Methyldopa inhibits the astrocyte-mediated protective effect of L-DOPA (HY-N0304) on dopaminergic neurons. In addition, 3-O-Methyldopa has certain antidepressant and neuroprotective activities. 3-O-Methyldopa can be used in the research of nervous system diseases such as depression and Parkinson's disease. | ||||||||||||||||||||
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3,4-Dihydroxymandelic acid (Standard) | ≥98% | 3,4-Dihydroxymandelic acid (Standard) is the analytical standard of 3,4-Dihydroxymandelic acid (HY-113474). This product is intended for research and analytical applications. 3,4‑Dihydroxymandelic acid is a metabolite of Norepinephrine (HY-13715) with free radical scavenging and antioxidant activities. 3,4-Dihydroxymandelic acid acts as a chemoattractant for enterohaemorrhagic Escherichia coli (EHEC), regulates virulence gene expression and bacterial adhesion to intestinal epithelial cells in a QseC-dependent manner, and targets EHEC to preferred infection sites. 3,4‑Dihydroxymandelic acid can be used in studies related to oxidative stress and enterohaemorrhagic Escherichia coli infection. | ||||||||||||||||||||
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(rac)-3-O-Methyl DOPA-d3 | 97.0% | (rac)-3-O-Methyl DOPA-d3 is the deuterium labeled (rac)-3-O-Methyl DOPA. | ||||||||||||||||||||
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3-Methoxy-4-hydroxyphenylglycolaldehyde | 3-Methoxy-4-hydroxyphenylglycolaldehyde is a nucleoside metabolite. | |||||||||||||||||||||
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(E)-Ferulic acid-d3 | 99.76% | (E)-Ferulic acid-d3 is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299. | ||||||||||||||||||||
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Apocynin-d3 | Apocynin-d3 is the deuterium labeled Apocynin. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM. | |||||||||||||||||||||
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Homovanillic acid | 99.54% | Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. | ||||||||||||||||||||
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Homovanillic acid-d3 | 99.85% | Homovanillic acid-d3 (Vanilacetic acid-d3) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. | ||||||||||||||||||||
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Vanillic acid | 99.45% | Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects. | ||||||||||||||||||||
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trans-Isoferulic acid-d3 | trans-Isoferulic acid-d3 is the deuterium labeled trans-Isoferulic acid. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity.trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1). | |||||||||||||||||||||
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Isovanillic acid (Standard) | ≥98% | Isovanillic acid (3-Hydroxy-4-methoxybenzoic acid) is a phenolic acid isolated from isolated from Scrophularia ningpoensis, with anti-thrombotic activity. | ||||||||||||||||||||
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(R)-3-O-Methyldopa-d3 | (R)-3-O-Methyldopa-d3 is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine. | |||||||||||||||||||||
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Homovanillic Acid-13C6 | Homovanillic Acid-13C6 (Vanilacetic acid-13C6) is the 13C-labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. | |||||||||||||||||||||
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Vanillic acid-13C6 | 99.9% | Vanillic acid-13C6 is the 13C labeled isotope of Vanillic acid-13C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities. | ||||||||||||||||||||
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4-O-Methyldopa-d3 | 4-O-Methyldopa-d3 is deuterium labeled 4-O-Methyldopamine. | |||||||||||||||||||||
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