3-Methoxy-4-hydroxyphenylglycol-d3
Based on 1 Customer Validation
3-Methoxy-4-hydroxyphenylglycol-d3 (HMPG-d3) is the deuterium labeled 3-Methoxy-4-hydroxyphenylglycol. 3-Methoxy-4-hydroxyphenylglycol is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol (HMPG) serves as an indicator of noradrenergic activity in the central nervous system. 3-Methoxy-4-hydroxyphenylglycol (HMPG) can be used for research on diseases such as depression and chronic schizophrenia.
For research use only. We do not sell to patients.
- Purity : 99.50%
- CAS No.: 74495-72-0
- Formula: C9H9D3O4
- Molecular Weight:187.21
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 74495-72-0
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Unlabeled CAS 534-82-7
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Appearance Solid
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Molecular Weight 187.21
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Formula C9H9D3O4
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Color White to off-white
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SMILES
OCC(C1=CC(OC([2H])([2H])[2H])=C(C=C1)O)O
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Synonyms
HMPG-d3; MHPG-d3; MOPEG-d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (534.16 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3416 mL | 26.7080 mL | 53.4159 mL | 133.5399 mL |
| 5 mM | 1.0683 mL | 5.3416 mL | 10.6832 mL | 26.7080 mL | |
| 10 mM | 0.5342 mL | 2.6708 mL | 5.3416 mL | 13.3540 mL | |
| 15 mM | 0.3561 mL | 1.7805 mL | 3.5611 mL | 8.9027 mL | |
| 20 mM | 0.2671 mL | 1.3354 mL | 2.6708 mL | 6.6770 mL | |
| 25 mM | 0.2137 mL | 1.0683 mL | 2.1366 mL | 5.3416 mL | |
| 30 mM | 0.1781 mL | 0.8903 mL | 1.7805 mL | 4.4513 mL | |
| 40 mM | 0.1335 mL | 0.6677 mL | 1.3354 mL | 3.3385 mL | |
| 50 mM | 0.1068 mL | 0.5342 mL | 1.0683 mL | 2.6708 mL | |
| 60 mM | 0.0890 mL | 0.4451 mL | 0.8903 mL | 2.2257 mL | |
| 80 mM | 0.0668 mL | 0.3338 mL | 0.6677 mL | 1.6692 mL | |
| 100 mM | 0.0534 mL | 0.2671 mL | 0.5342 mL | 1.3354 mL |
3-Methoxy-4-hydroxyphenylglycol-d3 Related Classifications
HY-113323S Related Classifications
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