Piroxicam-d3
Based on 1 Customer Validation
Piroxicam-d3 (CP-16171-d3) is deuterium labeled Piroxicam. Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively .
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 942047-64-5
- Formula: C15H10D3N3O4S
- Molecular Weight:334.36
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 942047-64-5
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Unlabeled Cas 36322-90-4
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Appearance Solid
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Molecular Weight 334.36
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Formula C15H10D3N3O4S
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Color Light yellow to yellow
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SMILES
O=C(C1=C(O)C2=CC=CC=C2S(N1C([2H])([2H])[2H])(=O)=O)NC3=NC=CC=C3
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Synonyms
CP-16171 d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (149.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 0.1 mg/mL (0.30 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9908 mL | 14.9539 mL | 29.9079 mL | 74.7697 mL |
| 5 mM | 0.5982 mL | 2.9908 mL | 5.9816 mL | 14.9539 mL | |
| 10 mM | 0.2991 mL | 1.4954 mL | 2.9908 mL | 7.4770 mL | |
| 15 mM | 0.1994 mL | 0.9969 mL | 1.9939 mL | 4.9846 mL | |
| 20 mM | 0.1495 mL | 0.7477 mL | 1.4954 mL | 3.7385 mL | |
| 25 mM | 0.1196 mL | 0.5982 mL | 1.1963 mL | 2.9908 mL | |
| 30 mM | 0.0997 mL | 0.4985 mL | 0.9969 mL | 2.4923 mL | |
| 40 mM | 0.0748 mL | 0.3738 mL | 0.7477 mL | 1.8692 mL | |
| 50 mM | 0.0598 mL | 0.2991 mL | 0.5982 mL | 1.4954 mL | |
| 60 mM | 0.0498 mL | 0.2492 mL | 0.4985 mL | 1.2462 mL | |
| 80 mM | 0.0374 mL | 0.1869 mL | 0.3738 mL | 0.9346 mL | |
| 100 mM | 0.0299 mL | 0.1495 mL | 0.2991 mL | 0.7477 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.