1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. p-Coumaric acid-d6

p-Coumaric acid-d6  (Synonyms: trans-4-Hydroxycinnamic acid-d6)

Cat. No.: HY-N0351S1 Purity: 98.88%
COA Handling Instructions

p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities[1][2].

For research use only. We do not sell to patients.

p-Coumaric acid-d<sub>6</sub> Chemical Structure

p-Coumaric acid-d6 Chemical Structure

CAS No. : 2708298-33-1

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5 mg USD 200 In-stock
10 mg USD 320 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

170.19

Formula

C9H2D6O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(/C([2H])=C([2H])/C1=C([2H])C([2H])=C(C([2H])=C1[2H])O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (587.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8758 mL 29.3789 mL 58.7579 mL
5 mM 1.1752 mL 5.8758 mL 11.7516 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.8758 mL 29.3789 mL 58.7579 mL 146.8946 mL
5 mM 1.1752 mL 5.8758 mL 11.7516 mL 29.3789 mL
10 mM 0.5876 mL 2.9379 mL 5.8758 mL 14.6895 mL
15 mM 0.3917 mL 1.9586 mL 3.9172 mL 9.7930 mL
20 mM 0.2938 mL 1.4689 mL 2.9379 mL 7.3447 mL
25 mM 0.2350 mL 1.1752 mL 2.3503 mL 5.8758 mL
30 mM 0.1959 mL 0.9793 mL 1.9586 mL 4.8965 mL
40 mM 0.1469 mL 0.7345 mL 1.4689 mL 3.6724 mL
50 mM 0.1175 mL 0.5876 mL 1.1752 mL 2.9379 mL
60 mM 0.0979 mL 0.4896 mL 0.9793 mL 2.4482 mL
80 mM 0.0734 mL 0.3672 mL 0.7345 mL 1.8362 mL
100 mM 0.0588 mL 0.2938 mL 0.5876 mL 1.4689 mL
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p-Coumaric acid-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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