2. Immunology/Inflammation Autophagy Anti-infection
  3. COX Autophagy Mitophagy Virus Protease
  4. Aspirin-d3

Aspirin-d3  (Synonyms: Acetylsalicylic Acid-d3; ASA-d3)

Cat. No.: HY-14654S Purity: 98.51%
COA Handling Instructions

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Aspirin-d3 is the deuterium labeled Aspirin. Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL.

For research use only. We do not sell to patients.

Aspirin-d<sub>3</sub> Chemical Structure

Aspirin-d3 Chemical Structure

CAS No. : 921943-73-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 176 In-stock
Solution
10 mM * 1 mL in DMSO USD 176 In-stock
Solid
1 mg USD 50 In-stock
5 mg USD 160 In-stock
10 mg USD 250 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Aspirin-d3:

Aspirin-d3 Related Antibodies

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Description

Aspirin-d3 is the deuterium labeled Aspirin. Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aspirin-d3 Related Antibodies
Molecular Weight

183.18

Formula

C9H5D3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=CC=C1OC(C([2H])([2H])[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (545.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4591 mL 27.2956 mL 54.5911 mL
5 mM 1.0918 mL 5.4591 mL 10.9182 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.51%

COA (253 KB) HNMR (264 KB) LCMS (89 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.4591 mL 27.2956 mL 54.5911 mL 136.4778 mL
5 mM 1.0918 mL 5.4591 mL 10.9182 mL 27.2956 mL
10 mM 0.5459 mL 2.7296 mL 5.4591 mL 13.6478 mL
15 mM 0.3639 mL 1.8197 mL 3.6394 mL 9.0985 mL
20 mM 0.2730 mL 1.3648 mL 2.7296 mL 6.8239 mL
25 mM 0.2184 mL 1.0918 mL 2.1836 mL 5.4591 mL
30 mM 0.1820 mL 0.9099 mL 1.8197 mL 4.5493 mL
40 mM 0.1365 mL 0.6824 mL 1.3648 mL 3.4119 mL
50 mM 0.1092 mL 0.5459 mL 1.0918 mL 2.7296 mL
60 mM 0.0910 mL 0.4549 mL 0.9099 mL 2.2746 mL
80 mM 0.0682 mL 0.3412 mL 0.6824 mL 1.7060 mL
100 mM 0.0546 mL 0.2730 mL 0.5459 mL 1.3648 mL
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Aspirin-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aspirin-d3921943-73-9Acetylsalicylic Acid-d3ASA-d3COXAutophagyMitophagyVirus ProteaseCyclooxygenaseMitochondrial AutophagyInhibitorinhibitorinhibit

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