2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Endogenous Metabolite
  4. 1-Methylguanosine-d3

1-Methylguanosine-d3  (Synonyms: N1-Methylguanosine-d3)

Cat. No.: HY-113136S Purity: 99.50%
COA
SDS
Handling Instructions Technical Support

1-Methylguanosine-d3 (N1-Methylguanosine-d3) is deuterium labeled 1-Methylguanosine (HY-113136). 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker.

For research use only. We do not sell to patients.

1-Methylguanosine-d<sub>3</sub>

1-Methylguanosine-d3 Chemical Structure

Size Price Stock Quantity
1 mg In-stock
5 mg Get quote 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
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50 mg   Get quote  

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Other Forms of 1-Methylguanosine-d3:

1-Methylguanosine-d3 Related Antibodies

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  • References

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Description

1-Methylguanosine-d3 (N1-Methylguanosine-d3) is deuterium labeled 1-Methylguanosine (HY-113136). 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1-Methylguanosine-d3 Related Antibodies
Molecular Weight

300.29

Formula

C11H12D3N5O5
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)N(C([2H])([2H])[2H])C3=O)=C3N=C2)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (166.51 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3301 mL 16.6506 mL 33.3011 mL
5 mM 0.6660 mL 3.3301 mL 6.6602 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.50%

SDS (394 KB)

COA (252 KB) Elemental Analysis Report (110 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.3301 mL 16.6506 mL 33.3011 mL 83.2529 mL
5 mM 0.6660 mL 3.3301 mL 6.6602 mL 16.6506 mL
10 mM 0.3330 mL 1.6651 mL 3.3301 mL 8.3253 mL
15 mM 0.2220 mL 1.1100 mL 2.2201 mL 5.5502 mL
20 mM 0.1665 mL 0.8325 mL 1.6651 mL 4.1626 mL
25 mM 0.1332 mL 0.6660 mL 1.3320 mL 3.3301 mL
30 mM 0.1110 mL 0.5550 mL 1.1100 mL 2.7751 mL
40 mM 0.0833 mL 0.4163 mL 0.8325 mL 2.0813 mL
50 mM 0.0666 mL 0.3330 mL 0.6660 mL 1.6651 mL
60 mM 0.0555 mL 0.2775 mL 0.5550 mL 1.3875 mL
80 mM 0.0416 mL 0.2081 mL 0.4163 mL 1.0407 mL
100 mM 0.0333 mL 0.1665 mL 0.3330 mL 0.8325 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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1-Methylguanosine-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Methylguanosine-d3N1-Methylguanosine-d3Isotope-Labeled CompoundsEndogenous MetaboliteInhibitorinhibitorinhibit

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