1. Immunology/Inflammation
    Metabolic Enzyme/Protease
  2. COX
    Endogenous Metabolite
  3. Valdecoxib-d3

Valdecoxib-d3  (Synonyms: SC 65872-d3)

Cat. No.: HY-15762S
Handling Instructions

Valdecoxib-d3 (SC 65872-d3) is the deuterium labeled Valdecoxib. Valdecoxib is a highly potent and selective inhibitor of COX-2, with IC50s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain.

For research use only. We do not sell to patients.

Valdecoxib-d3 Chemical Structure

Valdecoxib-d3 Chemical Structure

CAS No. : 1219794-90-7

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Description

Valdecoxib-d3 (SC 65872-d3) is the deuterium labeled Valdecoxib. Valdecoxib is a highly potent and selective inhibitor of COX-2, with IC50s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

317.38

Formula

C16H11D3N2O3S

CAS No.
SMILES

NS(C(C=C1)=CC=C1C(C(C2=CC=CC=C2)=NO3)=C3C([2H])([2H])[2H])(=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Valdecoxib-d3
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HY-15762S
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