Undecanoic acid-d21
Based on 1 Customer Validation
Undecanoic acid-d21 (Undecanoate-d21) is the deuterium labeled Undecanoic acid (HY-W004282). Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.80%
- CAS. Nr.: 60658-40-4
- Formel: C11HD21O2
- Molecular Weight:207.42
-
Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
-
Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS. Nr. 60658-40-4
-
Unlabeled CAS 112-37-8
-
Appearance Solid-Liquid Mixture
-
Molecular Weight 207.42
-
Formel C11HD21O2
-
Color White to off-white
-
SMILES
O=C(O)C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
-
Synonyms
Undecanoate-d21; Hendecanoic acid-d21
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (482.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
-
Data Sheet (275 KB)
-
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
-
Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Das SK, et al. Effect of undecanoic acid on phospholipid metabolism in Trichophyton rubrum. Sabouraudia. 1982 Dec;20(4):267-72. [Content Brief]
[3]. Das SK, et al. Effect of undecanoic acid on the production of exocellular lipolytic and keratinolytic enzymes by undecanoic acid-sensitive and -resistant strains of Trichophyton rubrum. Sabouraudia. 1982 Sep;20(3):179-84. [Content Brief]
[4]. Sathiyaseelan A, et al. Enhancing antifungal and biocompatible efficacy of undecanoic acid through incorporation with chitosan-based nanoemulsion. Int J Biol Macromol. 2024 May;267(Pt 1):131328. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8211 mL | 24.1057 mL | 48.2114 mL | 120.5284 mL |
| 5 mM | 0.9642 mL | 4.8211 mL | 9.6423 mL | 24.1057 mL | |
| 10 mM | 0.4821 mL | 2.4106 mL | 4.8211 mL | 12.0528 mL | |
| 15 mM | 0.3214 mL | 1.6070 mL | 3.2141 mL | 8.0352 mL | |
| 20 mM | 0.2411 mL | 1.2053 mL | 2.4106 mL | 6.0264 mL | |
| 25 mM | 0.1928 mL | 0.9642 mL | 1.9285 mL | 4.8211 mL | |
| 30 mM | 0.1607 mL | 0.8035 mL | 1.6070 mL | 4.0176 mL | |
| 40 mM | 0.1205 mL | 0.6026 mL | 1.2053 mL | 3.0132 mL | |
| 50 mM | 0.0964 mL | 0.4821 mL | 0.9642 mL | 2.4106 mL | |
| 60 mM | 0.0804 mL | 0.4018 mL | 0.8035 mL | 2.0088 mL | |
| 80 mM | 0.0603 mL | 0.3013 mL | 0.6026 mL | 1.5066 mL | |
| 100 mM | 0.0482 mL | 0.2411 mL | 0.4821 mL | 1.2053 mL |
Undecanoic acid-d21 Related Classifications
HY-W004282S Related Classifications
Powered by Bioz