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967

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

103

Natural
Products

254

Recombinant Proteins

Isotope-Labeled Compounds

125

Antibodies

Click Chemistry

Oligonucleotides

Vemurafenib 100+ Cited Publications PLX4032; RG7204; RO5185426	Raf Autophagy	Cancer
Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC₅₀s of 31 and 48 nM for RAF ^V600E and c-RAF-1, respectively . Vemurafenib induces cell autophagy .

V-9302 30+ Cited Publications	ASCT	Cancer
V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC₅₀=9.6 μM) in HEK-293 cells .

Mogroside V 5 Publications Verification	Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .

Ciforadenant 5+ Cited Publications CPI-444; V81444	Adenosine Receptor	Cancer
Ciforadenant (CPI-444) is a potent, orally active and selective adenosine A2A receptor (A2AR) antagonist, which induces antitumor responses .

V-9302 hydrochloride 30+ Cited Publications	ASCT	Cancer
V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake (IC₅₀=9.6 µM) in HEK-293 cells .

Penicillin V Potassium Phenoxymethylpenicillin potassium salt	Bacterial Antibiotic	Infection
Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis .

Bax inhibitor peptide V5 Maximum Cited Publications 16 Publications Verification BIP-V5; BAX Inhibiting Peptide V5	Bcl-2 Family Apoptosis	Cancer
Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.

Pocapavir 5 Publications Verification SCH-48973; V-073	Enterovirus	Infection
Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections .

Lixivaptan 4 Publications Verification VPA-985; WAY-VPA 985	Vasopressin Receptor	Cardiovascular Disease Endocrinology
Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC₅₀ values of 1.2 and 2.3 nM for human and rat V2, respectively.

Endoproteinase Glu-C (MS grade) V8 protease; Glu-C	Ser/Thr Protease	Others
Endoproteinase Glu-C (MS grade) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins .

RA-V	Wnt c-Myc Notch	Cancer
RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC₅₀ values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways .

Verucopeptin	HIF/HIF Prolyl-Hydroxylase Proton Pump Endogenous Metabolite	Cancer
Verucopeptin is a potent HIF-1 (IC50=0.22 μM) inhibitor and decreases the expression of HIF-1 target genes and HIF-1α protein levels. Verucopeptin strongly inhibits v-ATPase activity by directly targeting the v-ATPase ATP6V1G subunit but not ATP1V1B2 or ATP6V1D. Verucopeptin exhibits antitumor activity against multidrug resistance (MDR) cancers and can be used for cancer research.

V5 Epitope Tag Peptide TFA	Biochemical Assay Reagents	Others
V5 Epitope Tag Peptide TFA is a tag peptide derived from a small epitope present on the P and V proteins of the paramyxovirus of simian virus 5. V5 Epitope Tag Peptide TFA can be used for protein separation and purification, and competitive elution with target proteins .

Tradipitant VLY-686; LY686017	Neurokinin Receptor	Infection Neurological Disease Metabolic Disease
Tradipitant (VLY-686) is a neurokinin-1 (NK-1) antagonist.

SKI V 1 Publications Verification	SphK PI3K Apoptosis	Cancer
SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC₅₀ of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC₅₀ of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity .

WAY-151932 VNA-932; WAY-VNA 932	Vasopressin Receptor	Metabolic Disease Endocrinology
WAY-151932 is a vasopressin V₂-receptor agonist with IC₅₀ of 80.3 nM and 778 nM in human-V₂ binding and V_1a binding assay.

Tositumomab Anti-Human CD20 Recombinant Antibody; V10XA53	CD20	Cancer
Tositumomab (Anti-Human CD20 Recombinant Antibody) is a mouse-derived IgG2a monoclonal antibody, targeting to human CD20. Tositumomab can deplete B cells. Tositumomab can be used for the research of cancer, such as lymphoma .

Onvatilimab 1 Publications Verification JNJ-61610588; CI-8993; VSTB112	VISTA	Cancer
Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research .

VBY-825 1 Publications Verification	Cathepsin	Inflammation/Immunology Cancer
VBY-825 is an orally available novel reversible cathepsin inhibitor that has high inhibitory potency against cathepsin B, L, S and V, and possesses anti-tumor, anti-inflammatory and analgesic effects .

VPC-80051	DNA/RNA Synthesis	Cancer
VPC-80051 is an inhibitor of hnRNP A1 splicing activity. VPC-80051 directly interacts with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line. VPC-80051 can be used in prostate cancer research .

S65487 VOB560	Bcl-2 Family Apoptosis	Cancer
S65487 (VOB560), a potent and selective BCL-2 inhibitor, is a proagent of S55746. S65487 is also active on BCL-2 mutations, such as G101V and D103Y. S65487 has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 induces apoptosis and has anticaner activities .

VPC-70063	c-Myc PARP Apoptosis	Cancer
VPC-70063 is a potent Myc-Max inhibitor with an IC₅₀ value of 8.9 μM for Myc-Max transcriptional activity inhibition. VPC-70063 reduces UBE2C promotor activity and AR-V7 levels, and induces PARP cleavage. VPC-70063 induces apoptosis and blocks Myc-Max interactions with DNA. VPC-70063 can be used for researching anticancer .

VPC-14228	Androgen Receptor	Cancer
VPC-14228 is an inhibitor that selectively targets androgen receptor DNA binding domain (AR-DBD). VPC-14228 inhibits the interaction between AR and DNA, thereby blocking AR-mediated transcriptional activation. VPC-14228 does not rely on nuclear localization inhibition, but rather inhibits the activity of full-length AR and splice variant AR-V7 by interfering with AR binding to chromatin. And VPC-14228 has high selectivity for other nuclear receptors such as ER and PR. VPC-14228 can be used in the study of prostate cancer [2].

V-0219	GLP Receptor	Metabolic Disease Inflammation/Immunology
V-0219 is an orally active glucagon-like peptide-1 receptor (GLP-1R) positive allosteric modulator. V-0219 potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 potentiates glucose-dependent insulin secretion. V-0219 improves glucose handling in normal and diabetic rodents. V-0219 can be used for the research of obesity-associated diabetes .

V-11-0711	Choline Kinase Apoptosis	Cancer
V-11-0711 is a potent and selective Chk-α (IC₅₀ = 20 nM) inhibitor. V-11-0711 can significantly reduce PCho levels. V-11-0711 causes a reversible growth arrest. V-11-0711 induces apoptosis at high concentrations. V-11-0711 can be used for the study of cervical cancer and triple-negative breast cancer .

Myosin V-IN-1	Myosin	Neurological Disease
Myosin V-IN-1 (compound 8) is a potent and selective Myosin V inhibitor, with a K_i of 6 μM. Myosin V-IN-1 shows acute inhibition of myosin V. Myosin V-IN-1 slows the actin-activated myosin V ATPase by specifically inhibiting ADP release from the actomyosin complex .

Cap A (Acetonitrile/Acetic Anhydride, 80/20 v/v)	DNA/RNA Synthesis	Others
Cap A (Acetonitrile/Acetic Anhydride, 80/20 v/v) is a capping reagent that can be used in DNA/RNA synthesis .

Fedovapagon 1 Publications Verification VA106483	Vasopressin Receptor	Metabolic Disease
Fedovapagon (VA106483) is a selective and orally active vasopressin V2 receptor (V2R) agonist with an EC₅₀ of 24 nM. Fedovapagon can be used in the research of nocturia .

Flumioxazin Sumisoya; V-53482	Environmental Pollutants Herbicide	Others
Flumioxazin (Sumisoya) is an herbicide for use in soybean and peanut. Flumioxazin inhibits the enzyme protoporphyrinogen oxidase . Flumioxazin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Araloside V Congmunoside V	Others	Metabolic Disease
Araloside V (Congmunoside V) is a triterpenoid saponin isolated from Aralia elata .

V-0219 hydrochloride	GLP Receptor	Metabolic Disease Inflammation/Immunology
V-0219 hydrochloride is an orally active glucagon-like peptide-1 receptor (GLP-1R) positive allosteric modulator. V-0219 hydrochloride potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 hydrochloride potentiates glucose-dependent insulin secretion. V-0219 hydrochloride improves glucose handling in normal and diabetic rodents. V-0219 hydrochloride can be used for the research of obesity-associated diabetes .

Withanoside V	Amyloid-β Apoptosis Reactive Oxygen Species (ROS) SARS-CoV	Infection Neurological Disease
Withanoside V is a blood-brain barrier-permeable withanolide derivative . Withanoside V binds strongly to Sudlow I (domain IIA) of human serum albumin (HSA) to form a stable complex and alter the secondary structure of albumin, thereby increasing helix content and reducing β-sheet and random coil. Withanoside V binds to Aβ (1-42) to block the interaction between monomers and subsequent aggregation. Withanoside V inhibits the viability of neuroblastoma cells, reduces the number of apoptotic cells induced by Aβ (1-42), and decreases ROS production. Withanoside V inhibits SARS-CoV-2 M_pro. Withanoside V can be used for research on Alzheimer's disease and coronavirus disease 2019 .

Vem-L-Cy5	Raf	Cancer
Vem-L-Cy5 (compound 3)，modified with the NIR fluorophore cyanine-5 (Cy5)，is a Vemurafenib (HY-12057)-based inhibitor of BRAF. Vem-L-Cy5 targets to BRAF ^V600E，and also inhibits MEK phosphorylation. Vem-L-Cy5 has cell permeability，and inhibits cell growth of many types of cancer .

VISTA-IN-2	Autophagy	Inflammation/Immunology Cancer
VISTA-IN-2 (Compound 1) is an inhibitor of V-domain Ig suppressor of T-cell activation (VISTA). VISTA-IN-2 induces VISTA degradation in cells through an autophagic mechanism. VISTA-IN-2 rescues VISTA-mediated immunosuppression, and enhances antitumor activity of immune cells. VISTA-IN-2 also activates the antitumor immunity and inhibits tumor growth in a CT26 mouse model .

S65487 sulfate VOB560 sulfate	Bcl-2 Family Apoptosis	Cancer
S65487 (VOB560) sulfate, a potent and selective Bcl-2 inhibitor, is a proagent of S55746. S65487 sulfate is also active on BCL-2 mutations, such as G101V and D103Y. S65487 sulfate has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 sulfate induces apoptosis and has anticaner activities .

Cap B Acetonitrile/N-methylimidazole /pyridine, 50/20/30 v/v/v	Biochemical Assay Reagents	Others
Cap B (Acetonitrile/N-methylimidazole /pyridine, 50/20/30 v/v/v) is a biochemical reagent, which contains 50% Acetonitrile, 20 N-methylimidazole and 30% pyridine. Cap B (Acetonitrile/N-methylimidazole /pyridine, 50/20/30 v/v/v) is utilized as capping agent in oligonucleotide synthesis .

(R)-V-0219 hydrochloride	GLP Receptor	Metabolic Disease
(R)-V-0219 hydrochloride is an enantiomer of V-0219 (HY-143312). V-0219 is an orally active and positive allosteric modulator (PAM) of the GLP Receptor-1 (GLP-1R). (R)-V-0219 hydrochloride activates calcium fluxes in HEK cells stably expressing hGLP-1R .

(S)-V-0219 hydrochloride	GLP Receptor	Metabolic Disease
(S)-V-0219 hydrochloride is an enantiomer of V-0219 (HY-143312). V-0219 is an orally active and positive allosteric modulator (PAM) of the GLP Receptor-1 (GLP-1R). (S)-V-0219 hydrochloride activates calcium fluxes in HEK cells stably expressing hGLP-1R. (S)-V-0219 hydrochloride is orally active and ameliorates high glucose levels in mice and inhibits feeding behavior in fasted mice .

Platycodin V	Lipase	Metabolic Disease
Platycodin V is a triterpenoid saponin. Platycodin V has a relatively weak inhibitory effect on pancreatic lipase.

Cys-V5 Peptide	Biochemical Assay Reagents	Others
Cys-V5 Peptide, a tag peptide, is the V5 Peptide with an N-terminal cysteine. Cys-V5 Peptide can be used to label proteins

V023-9340	FXR	Metabolic Disease
V023-9340 is a potent FXR inhibitor with IC₅₀ of 4.27 μM that can be used in NASH (nonalcoholic steatohepatitis) research .

V-ATPase-IN-1	Proton Pump	Others
V-ATPase-IN-1 (Compound 3b-03) is a Vacuolar-type H ⁺-ATPases (V-ATPase) inhibitor (IC₅₀ = 194.80 μM) that can effectively target the *V-ATPase* subunit A (K_d = 0.803 μM). V-ATPase-IN-1 exhibits insecticidal activity against M. separata (LC₅₀ = 2.64 mM) and contributes to research in the development of chemical insecticides .

Co 102862 V 102862	Sodium Channel	Neurological Disease
Co 102862 (V 102862) is a potent, broad-spectrum, state-dependent Na ⁺ channel blocker. Co 102862 is also an orally active anticonvulsant .

vMIP-II (1-21) NT21MP; V1 peptide	CXCR	Inflammation/Immunology Cancer
vMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC₅₀=190 nM) .

2141-V11	TNF Receptor	Cancer
2141-V11 is an anti-CD40 agonist antibody with enhanced binding to FcγRIIB. 2141-V11 results in effective tumor-specific T-cell responses in vivo. 2141-V11 can be used for the study of BCG-unresponsive non-muscle invasive bladder cancer .

Vasopressin V2 receptor antagonist 1	Vasopressin Receptor	Endocrinology
Vasopressin V2 receptor antagonist 1 is a vasopressin V2 receptor (V₂R) antagonist with a K_i value of 3.8 nM. Vasopressin V2 receptor antagonist 1 inhibits renal cyst formation in embryonic renal cyst models and mouse models. Vasopressin V2 receptor antagonist 1 can be used in research related to autosomal dominant polycystic kidney disease .

Cat. No.	Product Name

HY-E0076

96-well Storage Plate	0 compounds
MCE 96-well storage plates are the ideal storage plate for compound library. Conical bottom (V) improves sample recovery and decreases dead volume. MCE 96-well storage plates are completely designed according to ANSI/SBS standards and can be adapted to various testing equipment and automatic workstations.

HY-L0122V

Asinex CNS Macrocycles Library

1,122 compounds

Several CNS multi-parameter scoring approaches have been reported: CNS-MPO, CNS-MPO V.2, CNS-TEMPO, which suggesting an algorithm to predict CNS-ike properties of new chemical entities. We have applied these scoring algorithms to select macrocycles satisfying multiple cut-offs and structural desirability criteria. The resulting set consists of 1,122 macrocyclic compounds with CNS-MPO > 4, CNS-MPO.v2 > 4, and CNS-TEMPO < 4 for CNS-related drug discovery and research.

HY-L260

KRAS Targeted Compound Library

32 compounds

KRAS (Kirsten Rat Sarcoma Viral Oncogene Homolog) is one of the most important oncogenic driver genes in oncology, with high mutation frequencies in pancreatic cancer, non‑small cell lung cancer, and colorectal cancer. For a long time, KRAS was considered "undruggable" due to the lack of suitable small‑molecule binding pockets on its protein surface. In recent years, with the discovery of the switch‑II pocket and the successful approval of KRAS G12C inhibitors, KRAS‑targeted research has achieved groundbreaking progress, which has also spurred a wave of development targeting non‑G12C mutants such as G12D and G12V, as well as upstream and downstream regulatory factors including SOS1 and SHP2.

MCE KRAS Targeted Compound Library contains 32 small‑molecule compounds targeting the KRAS, serving as high‑quality research tools for mechanistic studies of KRAS‑mutant tumors, combination therapy development, resistance mechanism exploration, and high‑throughput drug screening, thereby providing robust support for KRAS‑targeted drug discovery.

Cat. No.	Product Name	Type

HY-141601

Telisotuzumab vedotin 2 Publications Verification ABBV-399	Fluorescent Dyes
Telisotuzumab vedotin (ABBV-399) (Teliso-V) is an anti-c-Met antibody-drug conjugate. Telisotuzumab vedotin consists of an anti-c-Met monoclonal antibody Telisotuzumab (ABT-700) (HY-P99391) and Monomethyl Auristatin E (HY-15162). Telisotuzumab vedotin exerts antitumor activity with acceptable toxicity in vivo. Telisotuzumab vedotin can be used for non-small cell lung cancer (NSCLC) research .

HY-171821

PF-08046054 SGN-PDL1V	Fluorescent Dyes
PF-08046054 (SGN-PDL1V) is a PD-L1-directed Antibody-drug conjugate (ADC), which is comprised of an anti-PD-L1 antibody conjugated to VcMMAE (HY-15575). PF-08046054 is direct cytotoxicity to PD-L1-expressing tumor cells via the intracellular delivery of MMAE. PF-08046054 can be used for the study of solid tumors

HY-D0967

Cy5-bifunctional dye

Fluorescent Dyes

Cy5-bifunctional dye is a bifunctional dye used for covalent labeling of primary amines on proteins or oligonucleotides (Ex/Em = 649 nm/670 nm). Cy5-bifunctional dye can label recombinant annexin-V to assess phosphatidylserine exposure on the cell surface via flow cytometry. Cy5-bifunctional dye can label anti-human IgG (H + L) secondary antibodies. Cy5-bifunctional dye is applicable to studies of glanders and melioidosis .

HY-130210

Oxonol V	Fluorescent Dyes
Oxonol V is a slow-response sensitive probe for measuring cellular membrane potential.

HY-D1749

C6 NBD L-threo-ceramide	Fluorescent Dyes
C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.

HY-136784A

Rhod-2 sodium	Fluorescent Dyes
Rhod-2 sodium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 sodium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .

HY-136784

Rhod-2 potassium	Fluorescent Dyes
Rhod-2 potassium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 potassium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .

HY-D0293

Acid blue 1 free acid

Xylene blue free acid; C.I. Acid blue 1 free acid

Fluorescent Dyes

Acid blue 1 free acid (Patent Blue V) is a novel biological dye that can be used as an intraocular dye for retinectomy. Retinectomy refers to the removal of the translucent inner limiting membrane (ILM). The application of appropriate dyes in vitreoretinal surgery can achieve the purpose of complete removal. Acid blue 1 free acid can be used to stain retinal premembranous structures. Spectral analysis shows that Acid blue 1 free acid has strong absorption below 450 nm and above 600 nm, showing a blue-green color. Acid blue 1 free acid is also used as a marker in lymphangiography for resection of neoplastic lymph nodes .

HY-D2942

BDP-V BG-BODIPY

Fluorescent Dyes

BDP-V BG-BODIPY is a SNAP tag fluorescent probe labeled with a BODIPY molecular motor. BDP-V BG-BODIPY contains a BODIPY molecular rotor that functions as a viscosity-sensitive fluorophore, which is highly responsive to local viscosity changes and enables the specific monitoring of the local microviscosity of proteins. BDP-V BG-BODIPY supports one-photon and two-photon imaging, with an excitation wavelength (Ex) of 488 nm (for one-photon excitation) and 850 nm (for two-photon excitation), and an emission wavelength (Em) of 500-600 nm .

HY-D3118

Biotin-V	Fluorescent Dyes

HY-D3389

sCy5DL-amide

Fluorescent Dyes

sCy5DL-amide is an amidated fluorescent D-amino acid conjugated to Sulfo-Cyanine 5, and a peptidoglycan labeling agent. sCy5DL-amide incorporates into bacterial peptidoglycan cell wall via transpeptidase-mediated reactions, replacing the fourth or fifth D-amino acid of the peptidoglycan stem peptide for visualization of nascent peptidoglycan biosynthesis. sCy5DL-amide produces clear cell outline, septum labeling, and high localization density in Bacillus subtilis, including a 'V-shape' pattern at cell-cell contact areas. sCy5DL-amide exhibits robust incorporation into Gram-positive bacteria and mycobacteria, with reduced incorporation into Gram-negative bacteria (Ex/Em = 646/666 nm) .

Cat. No.	Product Name	Type

HY-A0104C

HPMC (Type I,Viscosity:400mPa.s) Hypromellose (Type I,Viscosity:400mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:400mPa.s); Celacol HPM 5000 (Type I,Viscosity:400mPa.s)	Biochemical Assay Reagents
HPMC (Hypromellose) (Type I, Viscosity: 400mPa.s) is a first-grade sodium alginate with an average viscosity of 400 mPa.s. Typically, a 1% w/v HPMC aqueous solution has a viscosity of 20-400mPa.s (20-400cp) at 20°C. The viscosity of HPMC may vary depending on concentration, pH, temperature, or the presence of metal ions. Viscosity decreases at pH values above 10 .

HY-W010929

PYR14-TFSI	Biochemical Assay Reagents
PYR14-TFSI is a room temperature ionic liquid (RTIL) with a wide electrochemical window (5.5V) and a high viscosity, making it a useful candidate for electrochemical energy applications .

HY-D0852A

Sodium metavanadate, 99% 1 Publications Verification Sodium vanadate(V), 99%	Biochemical Assay Reagents
Sodium metavanadate, 99% (Sodium vanadate(V), 99%) is a biochemical reagent used as a vanadium source in microbial cultures to study vanadium reduction in mesophilic and thermophilic methanogens .

HY-W002040

(±)-3-Amino-1,2-propanediol, 97% 1-Aminoglycerol, 97%	Biochemical Assay Reagents
(±)-3-Amino-1,2-propanediol, 97% (1-Aminoglycerol, 97%) is a chiral raw material that can be used for the synthesis of chiral vanadium (V) Schiff base complexes .

HY-Y1890B

Cremophor EL-10

Biochemical Assay Reagents

Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn ²⁺, Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses .

HY-W276164

Sodium octadecyl sulfate

Sodium stearyl sulfate

Biochemical Assay Reagents

Sodium octadecyl sulfate (Sodium stearyl sulfate) is a long-chain alkyl sodium sulfate that functions as an emulsifier, crosslinking agent, and regulator. Sodium octadecyl sulfate has high safety, with a LD₅₀ greater than 3.00 Gm./Kg for both intraperitoneal injection in mice and oral administration in rats. Sodium octadecyl sulfate enhances continuous contraction of the gastrocnemius muscle in frogs and boosts intestinal smooth muscle activity in albino rats. However, Sodium octadecyl sulfate exerts no significant effect on isolated tortoise myocardium and does not alter the conduction function of frog sciatic nerves. Sodium octadecyl sulfate can also be used to coat the surface of starch aggregates, promote crosslinking and increase aggregate size through hydrophobic and electrostatic interactions, and further form a coexistent B-V type crystalline structure with acid-hydrolyzed gelatinized starch, thereby effectively modifying the structure and surface properties of high-starch systems .

HY-W127781

Rhod-2 triammonium	Biochemical Assay Reagents
Rhod-2 triammonium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 triammonium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .

HY-NP111

Highly purified Type V collagen, from mouse intestine Mouse Type V collagen, immunization grade	Biochemical Assay Reagents
Highly purified Type V collagen, from mouse intestine (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse intestine, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-E70155

Fucosyltransferase 5 EC:2.4.1.65; Fucosyltransferase 5; Fucosyltransferase V	Biochemical Assay Reagents
Fucosyltransferase 5 (EC:2.4.1.65, Fucosyltransferase 5, Fucosyltransferase V) is responsible for the terminal step in the synthesis of Lex, sialy-Lex, and Lea antigens .

HY-157917

Nitro-PAPS disodium dihydrate	Biochemical Assay Reagents
Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V .

HY-NP104

Highly purified Type V collagen, from bovine amnion Bovine Amnion Type V collagen, immunization grade	Biochemical Assay Reagents
Highly purified Type V collagen, from bovine amnion (Bovine Amnion Type V collagen, immunization grade) is an immune grade collagen derived from bovine amnion, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

Cat. No.	Product Name	Target	Research Area

HY-P0049

Argipressin 5+ Cited Publications Arg8-vasopressin; AVP	Vasopressin Receptor	Neurological Disease Cancer
Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a K_d value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.

HY-P0003

Nesiritide Brain Natriuretic Peptide-32 human; BNP-32	Natriuretic Peptide Receptor (NPR) Calcium Channel	Cardiovascular Disease
Nesiritide (Brain Natriuretic Peptide-32 human) is a recombinant human B-type natriuretic peptide. Nesiritide is a NPRs agonist, with K_d values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Nesiritide regulates V_1/2 activation/inactivation of the L-type calcium channel. Nesiritide shows vasodilatory, diuretic, and natriuretic activities. Nesiritide is used in cardiovascular diseases such as heart failure and vascular remodeling after arterial injury .

HY-P0081

Bax inhibitor peptide V5 Maximum Cited Publications 16 Publications Verification BIP-V5; BAX Inhibiting Peptide V5	Bcl-2 Family Apoptosis	Cancer
Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.

HY-P2657

Verucopeptin	HIF/HIF Prolyl-Hydroxylase Proton Pump Endogenous Metabolite	Cancer
Verucopeptin is a potent HIF-1 (IC50=0.22 μM) inhibitor and decreases the expression of HIF-1 target genes and HIF-1α protein levels. Verucopeptin strongly inhibits v-ATPase activity by directly targeting the v-ATPase ATP6V1G subunit but not ATP1V1B2 or ATP6V1D. Verucopeptin exhibits antitumor activity against multidrug resistance (MDR) cancers and can be used for cancer research.

HY-105239

Selepressin FE 202158	Vasopressin Receptor	Cardiovascular Disease
Selepressin (FE 202158) is a selective *vasopressin V_1A* receptor** agonist. Selepressin is a potent vasopressor. Selepressin can be used in the research of septic shock .

HY-P0154

Epsilon-V1-2 5 Publications Verification ε-V1-2; EAVSLKPT	PKC	Inflammation/Immunology
Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocationof PKCε, but not α-, β-, and δPKC .

HY-P0325

V5 Epitope Tag Peptide TFA	Biochemical Assay Reagents	Others
V5 Epitope Tag Peptide TFA is a tag peptide derived from a small epitope present on the P and V proteins of the paramyxovirus of simian virus 5. V5 Epitope Tag Peptide TFA can be used for protein separation and purification, and competitive elution with target proteins .

HY-125747

Actinomycin X2 (purity≥85%) 1 Publications Verification Actinomycin V (purity≥85%)	Bacterial Antibiotic Apoptosis	Infection Cancer
Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection .

HY-W539944

Argipressin acetate 5+ Cited Publications Arg8-vasopressin acetate; AVP acetate	Vasopressin Receptor Apoptosis	Neurological Disease Cancer
Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a K_d value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .

HY-P3949

Fluorescent Substrate for Glu-Specific Proteases	Fluorescent Dye	Others
Fluorescent Substrate for Glu-Specific Proteases is a V8 protease-Specific chromogenic substrate .

HY-P0272

Peptide T	HIV	Infection
Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.

HY-P0083

Ornipressin POR-8	Vasopressin Receptor	Cardiovascular Disease
Ornipressin (POR-8) is a vasopressin agonist specific for the V1 receptor. Ornipressin can be used as a local vasoconstrictor. Ornipressin can reverse the hypotension associated with combine general/epidural anesthesia. Ornipressin has antidiuretic activity. Ornipressin decreases renal vascular resistance and increases renal blood flow in renal failure model .

HY-12554A

Terlipressin diacetate 2 Publications Verification	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-105239A

Selepressin acetate FE 202158 acetate	Vasopressin Receptor	Cardiovascular Disease
Selepressin (FE 202158) acetate is a selective *vasopressin V_1A* receptor** agonist. Selepressin acetate is a potent vasopressin. Selepressin acetate can be used in the study of septic shock.

HY-P5535

Invopressin OCE-205	Vasopressin Receptor	Inflammation/Immunology
Invopressin (Compound 42) is a vasopressin V1A receptor partial agonist (EC₅₀: 1.0 nM). Invopressin can be used for research of cirrhosis, including bacterial peritonitis, HRS2 and refractory ascites .

HY-P1785

Abl Cytosolic Substrate Abltide	Bcr-Abl	Cancer
Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ). Abl Protein Tyrosine Kinase (AbI) is a truncated form of the v-AbI Protein Tyrosine Kinase, a partner in the Gag-Abl fusion protein of the Abelson murine leukemia virus .

HY-P2265A

SAH-SOS1A TFA	SOS1 Ras	Cancer
SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC₅₀=106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS .

HY-P1390

d[Cha4]-AVP	Vasopressin Receptor	Endocrinology
d[Cha4]-AVP is a potent and selective vasopressin (AVP) V1b receptor agonist with a K_i of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .

HY-P1163A

D[LEU4,LYS8]-VP TFA	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
D[LEU4,LYS8]-VP TFA is a selective agonist of *vasopressin V_1b* receptor, with the K_is of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V_1b** receptor, respectively. D[LEU4,LYS8]-VP TFA has weak antidiuretic, vasopressor, and in vitro oxytocic activities .

HY-P3361A

IDR-1018 acetate	Parasite Bacterial Antibiotic	Infection Inflammation/Immunology
IDR-1018 acetate is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 acetate can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) .

HY-P5969

Cys-V5 Peptide	Biochemical Assay Reagents	Others
Cys-V5 Peptide, a tag peptide, is the V5 Peptide with an N-terminal cysteine. Cys-V5 Peptide can be used to label proteins

HY-P2478

Human PD-L1 inhibitor V	PD-1/PD-L1	Inflammation/Immunology
Human PD-L1 inhibitor V, a human PD-1 protein binding peptide with a K_d value of 3.32 μM. Human PD-L1 inhibitor V inhibit the interaction of hPD-1/hPD-L1 .

HY-P4109

vMIP-II (1-21) NT21MP; V1 peptide	CXCR	Inflammation/Immunology Cancer
vMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC₅₀=190 nM) .

HY-P4678

(Phe2,Orn8)-Oxytocin	Vasopressin Receptor	Neurological Disease
(Phe2,Orn8)-Oxytocin is a selective V1 vasopressin agonist. (Phe2,Orn8)-Oxytocin induces a sustained contractility of rabbit epididymis with EC₅₀ value of 280 nM .

HY-P3361

IDR-1018	Parasite Bacterial Antibiotic	Infection Inflammation/Immunology
IDR-1018 is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) .

HY-P0083A

Ornipressin acetate POR-8 acetate	Vasopressin Receptor	Cardiovascular Disease
Ornipressin (POR-8) acetate is a potent vasoconstrictor, hemostatic and renal agent. Ornipressin acetate is a vasopressin agonist specific for the V1 receptor. Ornipressin acetate can be used as a local vasoconstrictor. Ornipressin acetate can reverse the hypotension associated with combine general/epidural anesthesia. Ornipressin acetate has antidiuretic activity. Ornipressin acetate decreases renal vascular resistance and increases renal blood flow in renal failure model .

HY-P11356

KRAS G12V Peptide	IFNAR	Cancer
KRAS G12V Peptide is a specific peptide derived from the Kirsten rat sarcoma virus (KRAS) gene carrying the G12V oncogenic mutation. KRAS G12V Peptide induces responses like IFN-γ secretion and cytotoxicity. KRAS G12V Peptide can be used for the study of immune responses against KRAS G12V-mutant tumors .

HY-P11356A

KRAS G12V Peptide TFA	IFNAR	Cancer
KRAS G12V Peptide TFA is the trifluoroacetate salt of KRAS G12V Peptide (HY-P11355). KRAS G12V Peptide is a specific peptide derived from the Kirsten rat sarcoma virus (KRAS) gene carrying the G12V oncogenic mutation. KRAS G12V Peptide induces responses like IFN-γ secretion and cytotoxicity. KRAS G12V Peptide can be used for the study of immune responses against KRAS G12V-mutant tumors .

HY-P0049A

Argipressin diacetate Arg8-vasopressin diacetate; AVP diacetate; ADH	Apoptosis Vasopressin Receptor	Neurological Disease Cancer
Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes .

HY-P0162

HCV-IN-4	HCV	Infection
HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC₉₀s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively .

HY-P2265

SAH-SOS1A	SOS1 Ras	Cancer
SAH-SOS1A is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC₅₀=106-175 nM), directly and independently blocks nucleotide association, impairs KRAS-driven cancer cell viability, and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS .

HY-162394

Vasopressin V2 receptor antagonist 2	Vasopressin Receptor	Metabolic Disease
Vasopressin V2 receptor antagonist 2 (Compound 33) is an antagonist of the arginine vasopressin V₂ receptor (V₂R) with a K_i value of 6.2 nM. Vasopressin V2 receptor antagonist 2 can effectively reduce cAMP levels, thereby inhibiting the growth of renal cysts[1].

HY-P10947

MACTIDE-V	Epigenetic Reader Domain YAP	Cancer
MACTIDE-V is an orally active and selective peptide-drug conjugate targeting CD206. MACTIDE-V delivers Verteporfin (HY-B0146) to CD206 ⁺ tumor-associated macrophages (TAM) to inhibit the YAP/TAZ signaling pathway, prompting YAP exclusion from the nucleus, inducing TAM polarization toward an anti-tumoral phenotype with enhanced phagocytosis and antigen presentation, and boosting T cell infiltration and NK cell activity. MACTIDE-V suppresses primary tumor growth and lung metastasis in triple-negative breast cancer (TNBC) mouse models .

HY-P2548

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated	EGFR	Others
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification .

HY-P2478A

Human PD-L1 inhibitor V TFA	PD-1/PD-L1	Inflammation/Immunology
Human PD-L1 inhibitor V TFA, a human PD-1 protein binding peptide with a K_d value of 3.32 μM. Human PD-L1 inhibitor V TFA inhibit the interaction of hPD-1/hPD-L1 .

HY-P5989

Calpain inhibitor V Mu-Val-HPh-FMK	Antibiotic	Infection
Calpain inhibitor V (Mu-Val-HPh-FMK) is a cell-permeable and irreversible inhibitor of calpain that has anti-chlamydial activity .

HY-P5155

Stromatoxin 1	Potassium Channel	Neurological Disease
Stromatoxin 1 is an inhibitor of Potassium Channel, a peptide which can be isolated from tarantulas. Stromatoxin 1 selectively inhibits *K(V)2.1, K(V)2.2, K(V)4.2*, and K(V)2.1/9.3 channels. K(V)2.1 and K(V)2.2, but not K(V)4.2, channel subunits play a key role in opposing both myogenic and neurogenic urinary bladder smooth muscle (UBSM) contractions in rats .

HY-P1390A

d[Cha4]-AVP TFA	Vasopressin Receptor	Endocrinology
d[Cha4]-AVP TFA is a potent and selective vasopressin (AVP) V1b receptor agonist with a K_i of 1.2 nM for human V1b receptor. d[Cha4]-AVP TFA shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .

HY-P5010

(D-Arg8)-Inotocin	Vasopressin Receptor	Cardiovascular Disease
(D-Arg8)-Inotocin is a potent, selective and competitive antagonist of vasopressin receptor (V_1aR), with a K_i of 1.3 nM. (D-Arg8)-Inotocin shows more than 3000-fold selectivity for the human V1aR over the other three subtypes, OTR, V1bR and V2R .

HY-P5213

Vasopressin Dimer (parallel) TFA	Vasopressin Receptor Oxytocin Receptor	Endocrinology
Vasopressin Dimer (parallel) TFA is a parallel dimer of Vasopressin (HY-B1811). Vasopressin Dimer (parallel) TFA can activate four G protein-coupled receptors, *V1aR, V1bR, V2R, and OTR* .

HY-P1163

D[LEU4,LYS8]-VP	Vasopressin Receptor	Cardiovascular Disease Neurological Disease
D[LEU4,LYS8]-VP is a selective agonist of *vasopressin V_1b* receptor, with the K_is of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V_1b** receptor, respectively. D[LEU4,LYS8]-VP has weak antidiuretic, vasopressor, and in vitro oxytocic activities .

HY-P1737

Conopressin S Con-S	Peptides	Cardiovascular Disease
Conopressin S, isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a K_i of 8.3 nM .

HY-P0272A

Peptide T TFA	HIV	Infection
Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.

HY-P1162

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .

HY-P2636

Cholecystokinin Precursor (24-32) (rat) Prepro CCK Fragment V-9-M	Histamine Receptor	Metabolic Disease
Cholecystokinin Precursor (24-32) (rat) is a cholecystokinin precursor that can be expressed in the heart, lungs, and kidneys as well as in the gastrointestinal tract and brain. Cholecystokinin is a brain-gut peptide that stimulates gallbladder contraction and pancreatic exocrine secretion and also acts as a neurotransmitter .

HY-P2360

G12 Ras 5-17	Ras	Others
G12 (Ras 5-17) is a wild-type Ras peptide consisted of amino acids 5-17 (KLVVVGAGGVGKS). G12 can be used as a control of mutant Ras peptides studies (such V12) .

HY-P10325

Kalata B7	Vasopressin Receptor Oxytocin Receptor	Cardiovascular Disease
Kalata B7 is a cyclotide that can be isolated from Oldenlandia affinis DC (Rubiaceae) and possesses membrane-permeating capabilities. Kalata B7 is also a partial agonist of oxytocin and vasopressin V_1a receptors .

HY-P4109A

vMIP-II (1-21) TFA NT21MP TFA; V1 peptide TFA	CXCR	Inflammation/Immunology Cancer
vMIP-II (1-21) (NT21MP) TFA is an inhibitor of CXCR4. vMIP-II (1-21) TFA interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) TFA inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC₅₀=190 nM) .

HY-12554B

Terlipressin acetate	Vasopressin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology
Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .

HY-P5006

(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin d(CH2)5[Tyr(Me)2, Dab5]AVP	Vasopressin Receptor	Cardiovascular Disease
(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin (d(CH2)5[Tyr(Me)2, Dab5]AVP) is a specific antagonist of *vasopressin V_1a* receptor**, with a pA₂ of 6.71 .

Cat. No.	Product Name

HY-K1073

Annexin V-FITC/PI Apoptosis Detection Kit Maximum Cited Publications 66 Publications Verification
MCE Annexin V-FITC/PI Apoptosis Detection Kit provides a rapid and convenient method to detect cell apoptosis and necrosis. After staining, live cells show little or no fluorescence (Annexin V-/PI-), early apoptosis cells show green fluorescence(Annexin V+/PI-), late apoptosis cells and necrosis cells show red and green fluorescence (Annexin V+/PI+).

HY-K1080

Annexin V-iFluor 488/PI Apoptosis Detection Kit 1 Publications Verification
MCE Annexin V-iFluor 488/PI Apoptosis Detection Kit provides a rapid and convenient method to detect cell apoptosis and necrosis. After staining, live cells show little or no fluorescence (Annexin V-/PI-),, early apoptosis cells show green fluorescence (Annexin V+/PI-), late apoptosis cells and necrosis cells show red and green fluorescence (Annexin V+/PI+).

HY-K0249

Anti-V5 Magnetic Beads
MCE Anti-V5 Magnetic Beads are well suited for the detection and purification of V5-tagged fusion proteins, as well as for applications such as immunoprecipitation (IP) and co-immunoprecipitation (Co-IP). The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-K1093

VF 647A-Annexin V/PI Apoptosis Detection Kit 1 Publications Verification
MCE VF 647A-Annexin V/PI Apoptosis Detection Kit can be utilized to detect the level of cell apoptosis.

HY-K1096

Annexin V-FITC/7-AAD Apoptosis Detection Kit
MCE Annexin V-FITC/7-AAD Apoptosis Detection Kit can be utilized to detect the occurrence of early apoptosis.

HY-KE7015

EcoR V
MCE EcoR V is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Eco32 I.

HY-K1076

Annexin V-mCherry Apoptosis Detection Kit
Annexin V-mCherry Apoptosis Detection Kit provides a rapid and convenient method to detect cell apoptosis and necrosis. After staining, live cells show little or no fluorescence, apoptosis cells and necrosis cells show red fluorescence.

HY-K1075

Annexin V-PE Apoptosis Detection Kit 1 Publications Verification
MCE Annexin V-PE Apoptosis Detection Kit provides a rapid and convenient method to detect cell apoptosis and necrosis. After staining, live cells show little or no fluorescence, apoptosis cells and necrosis cells show red fluorescence.

HY-KE7008

BstB I
MCE BstB I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Asu II, Bpu14 I, Bsp119 I, BspT104 I, Nsp V, Sfu I.

HY-K1077

Annexin V-mCherry/SYTOX Green Apoptosis Detection Kit 2 Publications Verification
Annexin V-mCherry/SYTOX Green Apoptosis Detection Kit provides a rapid and convenient method to detect cell apoptosis and necrosis. After staining, live cells show little or no fluorescence, apoptosis cells show red fluorescence, necrosis cells show red and green fluorescence.

HY-E0209

384-well Storage Plate
MCE 384-well storage plate can be used for the storage of compound, and the V-shaped bottom design can improve the sample recovery rate and reduce the dead volume. This plate is made of polypropylene material with high heat resistance and free of detectable DNase, RNase, human DNA. ANSI/SBS compliant and suitable for automated pipette workstations and high-throughput screening platforms.

Cat. No.	Product Name	Target	Research Area	Image

HY-P99711

Loncastuximab RB4v1.2	CD19 ADC Antibody	Cancer
Loncastuximab (RB4v1.2) is an anti-CD19 monoclonal antibody. Loncastuximab has antitumor activity and can be used in the research of Non-Hodgkin Lymphoma (NHL) and Diffuse Large B-cell Lymphoma (DLBCL). Loncastuximab is capable of synthesizing the ADC molecule Loncastuximab tesirine (HY-P99349) .

HY-P99281

Bivatuzumab BIWA 4; Anti-CD44 Recombinant Antibody	Inhibitory Antibodies	Cancer
Bivatuzumab (Anti-CD44 Recombinant Antibody; BIWA 4) is a humanized monoclonal antibody directed against *CD44v6. CD44v6* could acts as a sarcoma target for CAR-redirected CIK cells .

HY-P991506

Fetrastobart SGN-PDL1V Antibody; PF-08046054 Antibody	ADC Antibody	Cancer
SGN-PDL1V Antibody is a PD-L1 targeting antibody. SGN-PDL1V Antibody can be used for synthesis of ADC SGN-PDL1V (HY-171821) .

HY-P99902

Simlukafusp alfa FAP-IL2v; RO6874281; RG7461	Interleukin Related	Cancer
Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAPα) and an IL-2 variant that only binds IL-2Rβγ. Isotype: human IgG1 .

HY-P99498

Cergutuzumab amunaleukin CEA-IL2v; RG 7813; RO 6895882	Interleukin Related	Inflammation/Immunology Cancer
Cergutuzumab amunaleukin (CEA-IL2v) is a monomeric carcinoembryonic antigen (CEA)-targeted IL-2 variant-based immunocytokine. Cergutuzumab amunaleukin has immunostimulating and antineoplastic activities .

HY-P99326

Tositumomab Anti-Human CD20 Recombinant Antibody; V10XA53	CD20	Cancer
Tositumomab (Anti-Human CD20 Recombinant Antibody) is a mouse-derived IgG2a monoclonal antibody, targeting to human CD20. Tositumomab can deplete B cells. Tositumomab can be used for the research of cancer, such as lymphoma .

HY-P99040

Onvatilimab 1 Publications Verification JNJ-61610588; CI-8993; VSTB112	VISTA	Cancer
Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research .

HY-P99395

Talacotuzumab 1 Publications Verification JNJ 56022473; CSL 362	Interleukin Related	Cancer
Talacotuzumab (JNJ 56022473; CSL 362) is an IgG1-type fully humanized, CD123-neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has K_Ds of 0.43 nM, 188 nM, 46 nM, 16.8 nM for CD123, CD32b/c, CD16-158F, CD16-158V, respectively. Talacotuzumab inhibits IL-3 binding to CD123, antagonizing IL-3 signaling in target cells. Talacotuzumab has mutated the Fc region to increase affinity for CD16 (FcγRIIIa), thereby enhancing antibody-dependent cell-mediated cytotoxicity (ADCC). Talacotuzumab is highly effective in vivo reducing leukemic cell growth in acute myeloid leukemia (AML) xenograft mouse models .

HY-P99490

Burfiralimab hzVSF-v13	Interleukin Related SARS-CoV	Infection Inflammation/Immunology
Burfiralimab (hzVSF-v13) is a monoclonal IgG4 antibody against vimentin expressed on the surface of virus-infected cells, with broad-spectrum antiviral activity and anti-inflammatory effects against virus-induced inflammation. Burfiralimab can be used in severe COVID-19 studies .

HY-P99308

Ocaratuzumab AME 133v; LY 2469298; Humanized Anti-MS4A1 Recombinant Antibody	CD20	Cancer
Ocaratuzumab (AME 133v) is an Fc-engineered humanized IgG1 anti-CD20 monoclonal antibody, with a K_d of ~100 pM. Ocaratuzumab exhibits more effective antibody-dependent cell-mediated cytotoxicity (ADCC) .

HY-P99102

Zinlirvimab 10-1074	HIV	Infection
Zinlirvimab is a human IgG1-λ2, HIV neutralising antibody targeting to HIV-1 gp120 envelope glycoprotein (IIIB gp120 V3 loop) .

HY-P991525

2141-V11	TNF Receptor	Cancer
2141-V11 is an anti-CD40 agonist antibody with enhanced binding to FcγRIIB. 2141-V11 results in effective tumor-specific T-cell responses in vivo. 2141-V11 can be used for the study of BCG-unresponsive non-muscle invasive bladder cancer .

HY-P990958

Invikafusp alfa	Inhibitory Antibodies	Inflammation/Immunology
HY-P990958 is an T cell receptor germline-encoded variable chain Vβ6/β10-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P991217

EU-103	Transmembrane Glycoprotein	Cancer
EU-103 is a humanized monoclonal antibody targeting V-Set And Immunoglobulin Domain Containing 4 (VSIG4) with a K_D value ranging from 10 ⁻⁷ and 10 ⁻⁹. EU-103 blocks the interaction between VSIG4 and CD8+ T cells, promotes the conversion of M2 macrophages into M1 macrophages, induces the proliferation of CD8+ T cells and the secretion of pro-inflammatory cytokines, thereby inhibiting tumor growth. EU-103 is promising for research of cancers, such as bladder cancer, breast cancer, and colon cancer .

HY-P991315

Anti-MSLN/Mesothelin (h7D9.v3) RG7600 antibody		Cancer
Anti-MSLN/Mesothelin (h7D9.v3) is a human monoclonal antibody (mAb) targeting MSLN. Anti-MSLN/Mesothelin (h7D9.v3) can be used in ovarian cancer, mesothelioma, and pancreatic cancer research .

HY-P990146

Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238)	Ras	Inflammation/Immunology
Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238) is an anti-mouse/rat/human *v-H-Ras* IgG2a monoclonal antibody. Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238) can be used as a control antibody. Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238) is often used for immunofluorescence and immunoprecipitation .

HY-P990113

Anti-Rat TCR gamma/delta Antibody (V65)	CD3	Inflammation/Immunology
Anti-Rat TCR gamma/delta Antibody (V65) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to rat TCR gamma/delta. Anti-Rat TCR gamma/delta Antibody (V65) can deplete γδ T cells. Anti-Rat TCR gamma/delta Antibody (V65) can be used for the research of immunology .

HY-P99147

Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6)	CD3	Infection Inflammation/Immunology
Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) is an Armenian Hamster-derived IgG antibody inhibitor, targeting to mouse TCR V gamma 2. Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) reacts with an epitope on the delta chain of the mouse Vγ2 TCR (V gamma 2 T cell receptor). Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) can deplete γδ T cell. Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) can be used for the researches of infection and immunology, such as herpes simplex virus-1 (HSV-1) infection .

HY-P990142

Anti-Mouse Vβ4 TCR Antibody (KT4)	MHC	Infection Inflammation/Immunology
Anti-Mouse Vβ4 TCR Antibody (KT4) is an anti-mouse Vβ4 TCR IgG2b monoclonal antibody. Anti-Mouse Vβ4 TCR Antibody (KT4) can reduce the proportion of Vβ4 ⁺ T cells without affecting their function. Anti-Mouse Vβ4 TCR Antibody (KT4) can be used for research on immunology and infection conditions such as virus infection. Anti-Mouse Vβ4 TCR Antibody (KT4) is often used in flow cytometry .

HY-P990141

Anti-Mouse Vβ8 TCR Antibody (F23.1)	MHC	Inflammation/Immunology
Anti-Mouse Vβ8 TCR Antibody (F23.1) is an anti-mouse Vβ8 TCR IgG2a monoclonal antibody. Anti-Mouse Vβ8 TCR Antibody (F23.1) can clear Vβ8 ⁺ T cells to alleviate immune conditions. Anti-Mouse Vβ8 TCR Antibody (F23.1) can be used for research on autoimmune conditions. Anti-Mouse Vβ8 TCR Antibody (F23.1) is often used in flow cytometry .

HY-P990161

Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11)	MHC	Inflammation/Immunology Cancer
Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) is an anti-mouse TCR Vγ1.1/Cr4 IgG monoclonal antibody. Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) can deplete Vγ1 γδ T cells. Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) can be used for research on cancer and inflammation conditions such as mastitis and colon cancer .

HY-P990065

Bremzalerbart	Inhibitory Antibodies	Others
Bremzalerbart is a human IgG4 antibody targeting BETVIA, the major birch pollen allergen Bet v 1-A .

HY-P990986

Efdelikofusp alfa	Interleukin Related	Inflammation/Immunology Cancer
Efdelikofusp alfa is a bispecific Fc fusion protein. Efdelikofusp alfa is formed by fusing the N-terminal extracellular domain of human CD80 (B7.1) with the Fc fragment of human immunoglobulin G4 (IgG4), and is linked to an interleukin-2 variant (IL-2v) as the C-terminal part. Efdelikofusp alfa exhibits potential immunostimulatory, immune checkpoint inhibitory, and antitumor activities.

HY-P990992

Efzilonkofusp alfa GI-102	Interleukin Related	Inflammation/Immunology Cancer
Efzilonkofusp alfa is a bispecific Fc fusion protein. Efzilonkofusp alfa is formed by fusing the N-terminal extracellular domain of human CD80 (B7.1) with the Fc fragment of human immunoglobulin G4 (IgG4), and is linked to an interleukin-2 variant (IL-2v) as the C-terminal part. Efzilonkofusp alfa exhibits potential immunostimulatory, immune checkpoint inhibitory, and antitumor activities.

HY-P990064

Umesolerbart	Inhibitory Antibodies	Inflammation/Immunology Cancer
Umesolerbart (REGN5714) is a Bet v1 specific mAb. Umesolerbart (REGN5714)bind to homologous allergens in Alder, Hazel and hornbeam .

HY-P991148

Moflerafusp alfa	PD-1/PD-L1	Cancer
Moflerafusp alfa is a fusion protein targeting the human signal regulatory protein α (SIRPα) variant V2 D1 domain and human programmed death ligand 1 (PD-L1). Moflerafusp alfa is promising for research of various cancers .

HY-P991991

Anti-Factor V Antibody	Thrombin	Cardiovascular Disease
Anti-Factor V Antibody is an anti-Factor V antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992152

Vatreptacog alfa	Factor VIIa Drug Derivative	Cardiovascular Disease
Vatreptacog alfa is a recombinant hFVIIa analog, differing from native FVIIa by three amino acid substitutions (V158D, E296V and M298Q) in the protease domain. Vatreptacog alfa exhibits enhanced tissue factor-independent enzymatic activity toward activated platelets. Vatreptacog alfa can be used in the research of hemophilia .

HY-P992414

MS17-38	Inhibitory Antibodies	Cancer
MS17-38 is a monoclonal antibody targeting *PODXL-v2. MS17-38 binds to a specific conformational epitope of PODXL-v2* on gastric cancer cells, modulates target function, inhibits gastric cancer cell growth and migration, and blocks tumor growth and lung metastasis. MS17-38 can be used for the research of gastric cancer .

HY-P991854

Anti-iNKT Cell Antibody (6B11)	Interleukin Related	Inflammation/Immunology
Anti-iNKT Cell Antibody (6B11) recognizes an epitope on T cell receptor (TCR) V alpha 24-J alpha 18. Anti-iNKT Cell Antibody is specific for cloned and primary human but not rodent iNKT and the human invariant TCR-α. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .

HY-P991922

AKIR001	Fc Receptor (FcR) Complement System Radionuclide-Drug Conjugates (RDCs)	Cancer
AKIR001 is a high-affinity human IgG1 antibody targeting *CD44v6. AKIR001 carries LALA-silencing mutations in its FcγR-binding domain to reduce FcγR* and C1q interactions, minimizing tissue interactions and limiting CDC and ADCC risks. [ ¹⁷⁷Lu] radiolabeled AKIR001, namely [ ¹⁷⁷Lu]Lu-AKIR001, has anticancer activity against epidermoid carcinoma .

Species:	Virus (23) Human (182) Rhesus Macaque (4) Rat (2) Mouse (30) Cynomolgus (10)
Tag:	SUMO (1) GST (46) Flag (2) His (189) Strep (6) Tag Free (24) Avi (53) Myc (2) HSA (2) HA (1) B2M (1) Fc (29) V5 (1)
Source:	HEK293 (158) E. coli Cell-free (2) CHO (1) sf9 insect cells (25) Sf9 insect cells (32) P. pastoris (1) E. coli (35)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P76159

	ATP6V1F Protein, Human (GST) V-type proton ATPase subunit F; V-ATPase subunit F; V-ATPase 14 kDa subunit; ATP6S14; VATF	Human	E. coli
	ATP6V1F is an important subunit of the vacuolar (H+)-ATPase (V-ATPase) V1 complex and is an important component of this enzyme's role in cellular pH regulation. It forms a catalytic AB heterodimer and peripheral stem that plays a role in ATP hydrolysis. ATP6V1F Protein, Human (GST) is the recombinant human-derived ATP6V1F protein, expressed by E. coli , with N-GST labeled tag.

HY-P77872

	Apolipoprotein A-V/APOA5 Protein, Mouse (His) Apolipoprotein A-V; Apo-AV; ApoA-V; Apolipoprotein A5; Apoa5; Rap3	Mouse	E. coli
	Apolipoprotein AV (APOA5) is primarily associated with HDL and VLDL, affecting triglyceride (TG) levels. APOA5 stimulates apo-CII lipoprotein lipase (LPL) TG hydrolysis and inhibits hepatic VLDL-TG production without affecting VLDL-apoB production. Apolipoprotein A-V/APOA5 Protein, Mouse (His) is the recombinant mouse-derived Apolipoprotein A-V/APOA5 protein, expressed by E. coli , with N-His labeled tag.

HY-P76159A

	ATP6V1F Protein, Human V-type proton ATPase subunit F	Human	E. coli
	ATP6V1F is an important subunit of the vacuolar (H+)-ATPase (V-ATPase) V1 complex and is an important component of this enzyme's role in cellular pH regulation. It forms a catalytic AB heterodimer and peripheral stem that plays a role in ATP hydrolysis. ATP6V1F Protein, Human is the recombinant human-derived ATP6V1F protein, expressed by E. coli , with tag free.

HY-P702861

	ATP6V0D1 Protein, Human (GST) V-type proton ATPase subunit d 1; V-ATPase subunit d 1; 32 kDa accessory protein; V-ATPase 40 kDa accessory protein; V-ATPase AC39 subunit (p39); Vacuolar proton pump subunit d 1	Human	E. coli
	ATP6V0D1 Protein, Human (GST) is the recombinant human-derived ATP6V0D1, expressed by E. coli, with N-GST labeled tag.

HY-P73868

	Integrin alpha V beta 3 Protein, Human (HEK293, His, solution) CD51; Integrin alpha V beta 3; integrin alpha-V; MSK8	Human	HEK293
	Integrin α V beta 3 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 3 Protein, Human (HEK293, His, solution) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 3 Protein, Human (HEK293, His, solution), has molecular weight of ~193.32 kDa.

HY-P72535

	Integrin alpha V beta 8 Protein, Human (HEK293, His) Integrin alpha V beta 8; ITGAV&ITGB8; Integrin alpha V beta 8 Heterodimer; Integrin Alpha V & Beta 8	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 8 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein, expressed by HEK293 , with C-6*His labeled tag. Integrin alpha V beta 8 Protein, Human (HEK293, His), has molecular weight of 125-160 & 80-100 kDa, respectively.

HY-P77721A

	Integrin alpha V beta 6 Protein, Human (HEK293, His) 1 Publications Verification CD51; Integrin alpha V beta 6; integrin subunit alpha V; ITGAV; MSK8; VNRA; VTNR	Human	HEK293
	Integrin alpha V beta 6 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 6 Protein, Human (HEK293, His), has molecular weight of ~130 & 95 KDa, respectively.

HY-P73867

	Integrin alpha V beta 6 Protein, Human (HEK293, Flag-His) CD51; Integrin alpha V beta 6; integrin subunit alpha V; ITGAV; MSK8; VNRA; VTNR	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 6 Protein, Human (HEK293, Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein, expressed by HEK293 , with C-His, C-Flag labeled tag. Integrin alpha V beta 6 Protein, Human (HEK293, Flag-His), has molecular weight of ~190.4 kDa.

HY-P700763

	Integrin alpha V beta 8 Protein, Mouse (HEK293, His) αVβ8; Integrin alpha V beta 8; ITGAV&ITGB8; Integrin alpha V β 8	Mouse	HEK293
	Integrin alpha V beta 3 (ITGAV:ITGB3) functions as a receptor for CD40LG, enhancing Lilrb4a inhibitory effects on mast cell activation. It suppresses marginal zone B cell antibody production through Lilrb4a interaction. ITGAV:ITGB3, forming a heterodimer with ITGAV, interacts with ligands such as RAB25, CIB1, FBLN5, and more. It also forms a complex with PTPRZ1 and PTN, stimulating endothelial cell migration. Integrin alpha V beta 8 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 8 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 8 Protein, Mouse (HEK293, His), has molecular weight of 80-140 kDa.

HY-P704726

	Integrin alpha V beta 6 Protein, Cynomolgus (HEK293, His) Integrin alpha V beta 6,ITGAV&ITGB6	Cynomolgus	HEK293

HY-P704727

	Integrin alpha V beta 5 Protein, Cynomolgus (HEK293, His) Integrin alpha V beta 5,ITGAV&ITGB5	Cynomolgus	HEK293

HY-P704728

	Integrin alpha V beta 1 Protein, Cynomolgus (HEK293, His) Integrin alpha V beta 1,ITGAV&ITGB1	Cynomolgus	HEK293

HY-P700762

	Integrin alpha V beta 6 Protein, Human (Biotinylated, HEK293, His-Avi) 1 Publications Verification αVβ6; Integrin alpha V beta 6; ITGAV&ITGB6; Integrin alpha V β 6	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 6 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 6 Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 90-150 kDa.

HY-P700767

	Integrin alpha V beta 8 Protein, Human (Biotinylated, HEK293, His-Avi) αVβ8; Integrin alpha V beta 8; TGAV&ITGB8; Integrin alpha V β 8	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 8 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 8 Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 85-145 kDa.

HY-P705051

	Integrin alpha V beta 8 Protein, Mouse (Biotinylated, HEK293, His-Avi) αVβ8; Integrin alpha V beta 8; ITGAV&ITGB8; Integrin alpha V β 8	Mouse	HEK293

HY-P703164

	Menin Protein, Human (His, M327V) SCG2	Human	E. coli
	The Menin protein is an important component of the MLL/SET1 HMT complex, which methylates “Lys-4” of histone H3. It acts as a transcriptional regulator, inhibiting telomerase expression and inhibiting cell proliferation through TGFB1. Menin Protein, Human (His, M327V) is the recombinant human-derived Menin, expressed by E. coli, with His labeled tag.

HY-P77723

	Integrin alpha V beta 6 Protein, Mouse (HEK293, His) ITGAV&ITGB6; Integrin alpha V beta 6	Mouse	HEK293
	Integrin alpha V beta 3 (ITGAV:ITGB3) functions as a receptor for CD40LG, enhancing Lilrb4a inhibitory effects on mast cell activation. It suppresses marginal zone B cell antibody production through Lilrb4a interaction. ITGAV:ITGB3, forming a heterodimer with ITGAV, interacts with ligands such as RAB25, CIB1, FBLN5, and more. It also forms a complex with PTPRZ1 and PTN, stimulating endothelial cell migration. Integrin alpha V beta 6 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 6 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 6 Protein, Mouse (HEK293, His), has molecular weight of 90-140 kDa.

HY-P702131

	COLAER_02088 Protein, Collinsella aerofaciens (T189V, V207M) 7beta-hydroxysteroid dehydrogenase; 7beta-HSDH; NADP-dependent 7beta-hydroxysteroid dehydrogenase	Others	E. coli
	The COLAER_02088 Protein, acting as a 7beta-hydroxysteroid dehydrogenase, transforms 7-oxo-lithocholate into chemopreventive UDCA in the human colon, showcasing its role in bile acid metabolism. This enzyme also exhibits reversible reactions, oxidizing UDCA and utilizing NADPH as its preferred electron acceptor, influencing bile acid dynamics and potential therapeutic applications. COLAER_02088 Protein, Collinsella aerofaciens (T189V, V207M) is the recombinant COLAER_02088 protein, expressed by E. coli , with tag free.

HY-P700760

	Integrin alpha V beta 3 Protein, Mouse (HEK293, hFc) αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3; Integrin alpha V β 3; β3	Mouse	HEK293
	Integrin alpha V beta 3 (ITGAV:ITGB3) functions as a receptor for CD40LG, enhancing Lilrb4a inhibitory effects on mast cell activation. It suppresses marginal zone B cell antibody production through Lilrb4a interaction. ITGAV:ITGB3, forming a heterodimer with ITGAV, interacts with ligands such as RAB25, CIB1, FBLN5, and more. It also forms a complex with PTPRZ1 and PTN, stimulating endothelial cell migration. Integrin alpha V beta 3 Protein, Mouse (HEK293, hFc) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 3 protein, expressed by HEK293 , with C-hFc labeled tag. Integrin alpha V beta 3 Protein, Mouse (HEK293, hFc), has molecular weight of 110-135 kDa & 50-60 kDa, respectively.

HY-P700761

	Integrin alpha V beta 3 Protein, Mouse (HEK293, His) αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3; Integrin alpha V β 3; β3	Mouse	HEK293
	Integrin alpha V beta 3 (ITGAV:ITGB3) functions as a receptor for CD40LG, enhancing Lilrb4a inhibitory effects on mast cell activation. It suppresses marginal zone B cell antibody production through Lilrb4a interaction. ITGAV:ITGB3, forming a heterodimer with ITGAV, interacts with ligands such as RAB25, CIB1, FBLN5, and more. It also forms a complex with PTPRZ1 and PTN, stimulating endothelial cell migration. Integrin alpha V beta 3 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 3 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 3 Protein, Mouse (HEK293, His), has molecular weight of 90-130 kDa.

HY-P701063

	Integrin alpha V beta 3 Protein, Cynomolgus (HEK293, His) αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3; Integrin alpha V β 3; β3	Cynomolgus	HEK293
	Integrin alpha V beta 3 Protein, part of the integrin alpha chain family, is highlighted. Integrin alpha V beta 3 Protein, Cynomolgus (HEK293, His) is a recombinant protein dimer complex containing cynomolgus-derived Integrin alpha V beta 3 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 3 Protein, Cynomolgus (HEK293, His), has molecular weight of 95-140 kDa.

HY-P77721

	Integrin alpha V beta 6 Protein, Human (HEK293, His-Avi) Integrin alpha V beta 6; ITGAV&ITGB6	Human	HEK293
	Integrin alpha V beta 6 Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein, expressed by HEK293 , with C-His, C-Avi labeled tag. Integrin alpha V beta 6 Protein, Human (HEK293, His-Avi), has molecular weight of 90-150 kDa.

HY-P77724

	Integrin alpha V beta 6 Protein, Rhesus Macaque (HEK293, His) ITGAV&ITGB6; Integrin alpha V beta 6	Rhesus Macaque	HEK293
	Integrin alpha V beta 6 Protein, part of the integrin alpha chain family, is featured. Integrin alpha V beta 6 Protein, Rhesus Macaque (HEK293, His) is a recombinant protein dimer complex containing Rhesus Macaque-derived Integrin alpha V beta 6 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 6 Protein, Rhesus Macaque (HEK293, His), has molecular weight of 90-140 kDa.

HY-P77722

	Integrin alpha V beta 8 Protein, Human (HEK293, His-Avi) Integrin alpha V beta 8; TGAV&ITGB8	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 8 Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 8 Protein, Human (HEK293, His-Avi), has molecular weight of 90-150 kDa.

HY-P77725

	Integrin alpha V beta 8 Protein, Rhesus Macaque (HEK293, His) Integrin alpha V beta 8; ITGAV&ITGB8	Rhesus Macaque	HEK293
	Integrin alpha V beta 6 Protein, part of the integrin alpha chain family, is featured. Integrin alpha V beta 8 Protein, Rhesus Macaque (HEK293, His) is a recombinant protein dimer complex containing Rhesus Macaque-derived Integrin alpha V beta 8 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 8 Protein, Rhesus Macaque (HEK293, His), has molecular weight of 90-140 kDa.

HY-P702132

	COLAER_02088 Protein, Collinsella aerofaciens (T189V, V207M, GST) 7beta-hydroxysteroid dehydrogenase; 7beta-HSDH; NADP-dependent 7beta-hydroxysteroid dehydrogenase	Others	E. coli
	The COLAER_02088 Protein, acting as a 7beta-hydroxysteroid dehydrogenase, transforms 7-oxo-lithocholate into chemopreventive UDCA in the human colon, showcasing its role in bile acid metabolism. This enzyme also exhibits reversible reactions, oxidizing UDCA and utilizing NADPH as its preferred electron acceptor, influencing bile acid dynamics and potential therapeutic applications. COLAER_02088 Protein, Collinsella aerofaciens (T189V, V207M, GST) is the recombinant COLAER_02088 protein, expressed by E. coli , with N-GST labeled tag.

HY-P75927

	MGAT5 Protein, Human (HEK293, His) Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; GNT-V; Secreted GNT-V; MGAT5; GGNT5	Human	HEK293
	The MGAT5 protein regulates the cytoskeleton, adhesion, migration, and signaling. MGAT5 Protein, Human (HEK293, His) is the recombinant human-derived MGAT5 protein, expressed by HEK293 , with C-His labeled tag.

HY-P704069

	Integrin alpha V Protein, Human (P. pastoris, His) Integrin alpha-V; ITGAV; Vitronectin receptor; Vitronectin receptor subunit alpha; CD51; ITGAV; MSK8; VNRA; VTNR	Human	P. pastoris

HY-P705050

	Integrin alpha V beta 6 Protein, Mouse (Biotinylated, HEK293, His-Avi) ITGAV&ITGB6; Integrin alpha V beta 6	Mouse	HEK293

HY-P705052

	Integrin alpha V beta 5 Protein, Mouse (Biotinylated, HEK293, His-Avi) Integrin alpha V beta 5; ITGAV&ITGB5	Mouse	HEK293

HY-P700765

	Integrin alpha V beta 3 Protein, Human (Biotinylated, HEK293, His-Avi) αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3; Integrin alpha V β 3; β3	Human	HEK293
	Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha V beta 3 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 3 Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 90-160 kDa.

HY-P700766

	Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi) αVβ5; Integrin alpha V beta 5; beta5; alphaV; ITGAV&ITGB5; Integrin alpha V β 5; β5	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 85-140 kDa.

HY-P701015

	Integrin alpha V beta 3 Protein, Mouse (Biotinylated, HEK293, His-Avi) αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3; Integrin alpha V β 3; β3	Mouse	HEK293
	Integrin alpha V beta 3 (ITGAV:ITGB3) functions as a receptor for CD40LG, enhancing Lilrb4a inhibitory effects on mast cell activation. It suppresses marginal zone B cell antibody production through Lilrb4a interaction. ITGAV:ITGB3, forming a heterodimer with ITGAV, interacts with ligands such as RAB25, CIB1, FBLN5, and more. It also forms a complex with PTPRZ1 and PTN, stimulating endothelial cell migration. Integrin alpha V beta 3 Protein, Mouse (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 3 Protein, Mouse (Biotinylated, HEK293, His-Avi), has molecular weight of 90-130 kDa.

HY-P73865

	Integrin alpha V beta 8 Protein, Human (HEK293, His, solution) Integrin alpha V beta 8; CD51; ITGAV; ITGB8	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 8 Protein, Human (HEK293, His, solution) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha V beta 8 Protein, Human (HEK293, His, solution), has molecular weight of ~187.95 kDa.

HY-P76539

	PF4V1 Protein, Human (HEK293, Fc) Platelet factor 4 variant; CXCL4L1; PF4var1; SCYB4V1	Human	HEK293
	PF4V1, also known as CXCL4L1, is a non-allelic variant of CXCL4. PF4V1 is a platelet-associated chemokine, and it binds to heparin is much weaker than in the close homolog PF4/CXCL4. PF4V1 is an inhibitor of angiogenesis and inhibitor of endothelial cell chemotaxis. PF4V1 is involved in inflammation, angiogenesis, and cancer. PF4V1 Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 104 amino acids (M1-S104).

HY-P70234

	Kras4B Protein, Human (G12V, His) rHuGTPase Kras4B-G12V, His; Ki-Ras; c-K-ras; KRAS2; RASK2; CFC2	Human	E. coli
	The Kras4B protein interacts specifically with GPR31, dependent on farnesylation. This binding suggests a regulatory role for Kras4B in association with GPR31, emphasizing the importance of the farnesylation process. Comprehensive exploration into the molecular details of this interaction is crucial to understand the precise mechanisms and functional implications in cellular processes or signaling pathways. Kras4B Protein, Human (G12V, His) is the recombinant human-derived Kras4B protein, expressed by E. coli , with N-6*His labeled tag.

HY-P73764

	NA/Neuraminidase Protein, H3N2 (E119V, ACN50232, HEK293) NA; Neuraminidase; NA/Neuraminidase Protein, H3N2 (E119V, HEK293)	Virus	HEK293
	NA/Neuraminidase Protein is a receptor-destroying enzyme that cleaves terminal sialic acids from cellular receptors, potentially facilitating viral invasion of the upper airways by targeting sialic acid moieties on airway epithelial cell mucin. NA plays a pivotal role in viral propagation by catalyzing the removal of terminal sialic acid residues from both viral and cellular glycoconjugates. Moreover, the sialidase activity in late endosome/lysosome traffic appears to enhance virus replication. NA/Neuraminidase Protein, H3N2 (E119V, ACN50232, HEK293) is the recombinant Virus-derived NA/Neuraminidase protein, expressed by HEK293 , with tag free. It originates from cell lysates collected after expressing a DNA sequence encoding the Influenza A virus neuraminidase.

HY-P71410

	UBE2V1 Protein, Human (His) Ubiquitin-Conjugating Enzyme E2 Variant 1; UEV-1; CROC-1; TRAF6-Regulated IKK Activator 1 Beta Uev1A; UBE2V1; CROC1; UBE2V; UEV1; P/OKcl.19	Human	E. coli
	The UBE2V1 protein does not have intrinsic ubiquitin ligase activity and can cooperate with UBE2N to synthesize non-canonical polyubiquitin chains linked through Lys-63. This type of polyubiquitination activates IKK and mediates NF-kappa-B activation, thereby affecting transcriptional activation, cell cycle progression, and DNA repair. UBE2V1 Protein, Human (His) is the recombinant human-derived UBE2V1 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P77719

	Integrin alpha V beta 3 Protein, Human (HEK293, His-Avi) 1 Publications Verification Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3	Human	HEK293
	Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha V beta 3 Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein, expressed by HEK293, with C-His, C-Avi labeled tag. Integrin alpha V beta 3 Protein, Human (HEK293, His-Avi), has molecular weight of 85-140 kDa.

HY-P77720

	Integrin alpha V beta 5 Protein, Human (HEK293, His-Avi) 1 Publications Verification Integrin alpha V beta 5; beta5; alphaV; ITGAV&ITGB5	Human	HEK293
	Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 5 Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 5 Protein, Human (HEK293, His-Avi), has molecular weight of 85-160 kDa.

HY-P705737

	BRAF Protein, Human (Active, G464V, sf9, His-GST) BRAF1; RAFB; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1	Human	sf9 insect cells

HY-P705740

	BRAF Protein, Human (Active, L597V, sf9, His-GST) BRAF1; RAFB; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1	Human	sf9 insect cells

HY-P701179

	FUBP1 Protein, Human (HEK293, C-His) FBP; FUBP; hDH V	Human	HEK293
	FUBP1 Protein, a pivotal regulator of MYC expression, binds to the far-upstream element (FUSE) upstream of the MYC promoter, dynamically acting as both an activator and repressor of gene expression. It forms a complex with PUF60, associated with FUSE DNA, implying involvement in intricate molecular processes. Interaction with PUF60 and JTV1 suggests potential cooperative actions in gene expression modulation. FUBP1 Protein, Human (HEK293, C-His) is the recombinant human-derived FUBP1 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P705678

	Cathepsin B Protein, Human (L26V, HEK293) CTSB; CPSB; APPS	Human	HEK293
	Cathepsin B Protein, a thiol protease, is crucial for intracellular protein degradation, cleaving matrix extracellular phosphoglycoprotein MEPE. It's implicated in solubilizing cross-linked TG/thyroglobulin in the thyroid follicle lumen. Associated with tumor invasion and metastasis, Cathepsin B signifies potential relevance in cancer-related pathways. Cathepsin B Protein, Human (L26V, HEK293) is the recombinant human-derived Cathepsin B protein, expressed by HEK293 , with L26V mutation.

HY-P703978

	Serum Albumin/ALB Protein, Human (HEK293, V418M, T420A, E505G, V547A) Albumin; ALB; Serum albumin; ANALBA; FDAH; PRO0883; PRO0903; PRO1341	Human	HEK293
	The serum albumin/ALB protein has multiple binding abilities and can bind water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin, and drugs. Its main effects include regulating blood colloid osmotic pressure to achieve homeostasis. Serum Albumin/ALB Protein, Human (HEK293, V418M, T420A, E505G, V547A) is the recombinant human-derived Serum Albumin/ALB protein, expressed by HEK293, with tag free.

HY-P78682

	Cathepsin B Protein, Human (L26V, HEK293, His) 1 Publications Verification CTSB; CPSB; APPS	Human	HEK293
	Cathepsin B Protein, a thiol protease, is crucial for intracellular protein degradation, cleaving matrix extracellular phosphoglycoprotein MEPE. It's implicated in solubilizing cross-linked TG/thyroglobulin in the thyroid follicle lumen. Associated with tumor invasion and metastasis, Cathepsin B signifies potential relevance in cancer-related pathways. Cathepsin B Protein, Human (L26V, HEK293, His) is the recombinant human-derived Cathepsin B protein, expressed by HEK293 , with C-His labeled tag and L26V mutation.

HY-P77210

	Sorcin/SRI Protein, Human (sf9) 22 kDa protein; CP22; V19	Human	Sf9 insect cells
	The Sorcin/SRI protein is a calcium-binding regulator that complexly regulates excitation-contraction coupling in the heart and plays a critical role in maintaining calcium homeostasis within the sarcoplasmic reticulum. As a homodimer, Sorcin/SRI affects the activity of the RYR2 calcium channel, helping to precisely control calcium dynamics in cardiomyocytes. Sorcin/SRI Protein, Human (sf9) is the recombinant human-derived Sorcin/SRI protein, expressed by Sf9 insect cells , with tag free.

HY-P704725

	Integrin alpha V beta 8 Protein, Cynomolgus (HEK293, His)	Cynomolgus	HEK293

HY-P72564

	IL-2 Protein, Human (L100F, R101D, L105V, I106V, I112F, HEK293, His) Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin	Human	HEK293
	IL-2 protein is mainly produced by activated CD4-positive helper T cells and plays an important role in immune response and tolerance. Binding to IL-2R induces downstream signaling through JAK1 and JAK3 phosphorylation, thereby activating various pathways, including STAT, PI3K, and MAPK. IL-2 Protein, Human (L100F, R101D, L105V, I106V, I112F, HEK293, His) is the recombinant human-derived IL-2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P705321

	*HLA-A02:01&B2M&KRAS G12V(KLVVVGAVGV) Monomer Protein, Human (Biotinylated, HEK293, His-Avi)** HLA-A*0201 & B2M & KRASG12V (KLVVVGAVGV)	Human	HEK293

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Host:	Mouse (49) Rat (1) Rabbit (75)
Reactivity:	Human (115) mouse (1) rat (1) Rat (65) Mouse (70) Monkey (2) Species independent (3) human (5)
Application:	IHC-P (81) ICC/IF (50) mIHC (1) IF-Tissue (15) IP (31) WB (91) IHC-F (16) ChIP (1) FC (25) ELISA (26)
Isotype:	IgG (74) IgG1 (27) IgG2a (7) IgG/Kappa (2) IgG2b (9)
Conjugation:	AF 594 (1) Non-conjugated (124) Biotin (39)
Clonality:	Polyclonal (12) Monoclonal (71) Monoclonal Antibody (3) Recombinant (40)
Modification:	Phosphorylated (8) Unmodified (84)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87143

	VIP Antibody (YA6836) Peptide histidine methioninamide 27 antibody; Peptide histidine valine 42 antibody; PHM27 antibody; PHV42 antibody; Prepro V; IP : antibody; Vasoactive intestinal peptide antibody; Vasoactive intestinal polypeptide antibody; V; IP : antibody; V; IP : peptides antibody; V; IP : peptides precursor antibody; Peptide histidine methioninamide 27 antibody; Peptide histidine valine 42 antibody; PHM27 antibody; PHV42 antibody; Prepro V; IP : antibody; Vasoactive intestinal peptide antibody; Vasoactive intestinal polypeptide antibody; V; IP : antibody; V; IP : peptides antibody; V; IP : peptides precursor antibody; VIP_HUMAN antibody;	IHC-F, IHC-P	Human, Mouse, Rat
	VIP Antibody (YA6836) is a Rat -derived and non-conjugated monoclonal antibody, targeting to VIP.

HY-P82801

	RASGRP1 Antibody (YA2546) V; RASGRP; hRasGRP1; CALDAG-GEFI; CALDAG-GEFII	WB	Human
	RASGRP1 Antibody (YA2546) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RASGRP1.

HY-P82801A

	RASGRP1 Antibody (YA2546)(PBS only) V; RASGRP; hRasGRP1; CALDAG-GEFI; CALDAG-GEFII	WB	Human
	RASGRP1 Antibody (YA2546) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RASGRP1.

HY-P85346

	RAG-2 Antibody (YA5038) RAG2; V; D; J recombination-activating protein 2; RAG-2	WB	Human, Mouse
	RAG-2 Antibody (YA5038) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to RAG-2.

HY-P89402

	V5-tag Antibody (YA8852)(AF594) V5-tag	ICC/IF	Species independent
	V5 Tag Antibody (YA8852) is a non-conjugated and Rabbit origined IgG monoclonal antibody, targeting to V5-tag.

HY-P89135

	GH2 Antibody (YA8819) GH-V; GHB2; GHL; GHV; hGH-V	IHC-P	Human
	GH2 Antibody (YA8819) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to GH2.

HY-P89635

	Factor V Antibody (YA8979) Coagulation factor V, Activated protein C cofactor, F5	WB, ICC/IF, IF-Tissue, IP, ELISA	human
	Factor V Antibody (YA8979) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Factor V.

HY-P811281

	Vasopressin V1a Receptor Antibody AVPR1, AVPR1A, Vasopressin V1a receptor, V1aR, AVPR V1a, Antidiuretic hormone receptor 1a, Vascular/hepatic-type arginine vasopressin receptor	WB, ICC/IF	Human, Mouse, Rat
	Vasopressin V1a Receptor Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Vasopressin V1a Receptor.

HY-P89135A

	GH2 Antibody (YA8819)(PBS only) GH-V; GHB2; GHL; GHV; hGH-V	IHC-P	Human
	GH2 Antibody (YA8819) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to GH2.

HY-P811050

	ATP6V0A2 Antibody V-type proton ATPase 116 kDa subunit a 2, V-ATPase 116 kDa subunit a 2, Lysosomal H(+)-transporting ATPase V0 subunit a 2, TJ6, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2, ATP6V0A2	WB, ICC/IF	Human, Mouse, Rat
	ATP6V0A2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to ATP6V0A2.

HY-P810089

	Rho V Antibody (YA9433)	WB, ICC/IF, IF-Tissue, IP, ELISA	human, mouse, rat
	Rho V Antibody (YA9433) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Rho V.

HY-P810986

	ATP6V1H Antibody CGI-11, ATP6V1H, V-type proton ATPase subunit H, V-ATPase subunit H, Nef-binding protein 1, Protein VMA13 homolog, V-ATPase 50/57 kDa subunits, Vacuolar proton pump subunit H, Vacuolar proton pump subunit SFD, NBP1	WB, IHC-P	Human, Mouse, Rat
	ATP6V1H Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to ATP6V1H.

HY-P80367

	V5-tag Antibody (YA656)	WB, ELISA	Species independent
	V5-tag Antibody (YA656) is a non-conjugated and Mouse origined IgG1 monoclonal antibody, targeting to V5-tag.

HY-P80417

	Integrin alpha V Antibody (YA338)	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Integrin alpha V Antibody (YA338) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin alpha V.

HY-P87167

	V5 Tag Antibody (YA6860)	WB, ICC/IF, IP	Species independent
	V5 Tag Antibody (YA6860) is a non-conjugated and Rabbit origined IgG monoclonal antibody, targeting to V5-tag.

HY-P86628

	Lactate Dehydrogenase Isoenzyme V Antibody (YA6320)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Lactate Dehydrogenase Isoenzyme V Antibody (YA6320) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Lactate Dehydrogenase Isoenzyme V.

HY-P89802

	CYP4V2 Antibody (YA9146)	WB, IP, ELISA	human
	CYP4V2 Antibody (YA9146) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CYP4V2.

HY-P810496

	FUBP1 Antibody (YA9789) DNA helicase V, FBP, FUBP, Fubp1, Fubp4, FUSE-binding protein 1, HDH V	WB, IHC-F, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat
	FUBP1 Antibody (YA9789) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to FUBP1.

HY-P89836

	AVP Receptor V1a Antibody (YA9180)	WB, IP, ELISA	human
	AVP Receptor V1a Antibody (YA9180) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to AVP Receptor V1a.

HY-P81374

	FUBP1 Antibody (YA1119) DNA helicase V; FBP; FUBP; Fubp1; Fubp4; FUSE-binding protein 1; HDH V	IHC-P	Human
	FUBP1 Antibody (YA1119) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FUBP1.

HY-P81374A

	FUBP1 Antibody (YA1119)(PBS only) DNA helicase V; FBP; FUBP; Fubp1; Fubp4; FUSE-binding protein 1; HDH V	IHC-P	Human
	FUBP1 Antibody (YA1119) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FUBP1.

HY-P88302

	PYGM Antibody (YA7986) glycogen; glycogen phosphorylase; glycogen storage disease type V; glycogen storage disease type V); McArdle syndrome; muscle; muscle (McArdle syndrome; myophosphorylase; phosphorylase	IHC-P	Human, Rat, Mouse
	PYGM Antibody (YA7986) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYGM.

HY-P84641

	Apoa5 Antibody (YA4338) RAP3; APOAV; APOA-V	WB, ELISA	Human
	Apoa5 Antibody (YA4338) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Apoa5.

HY-P86133

	VCAM1 Antibody (YA5825) Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD antigen CD106;	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	VCAM1 Antibody (YA5825) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VCAM1.

HY-P88302A

	PYGM Antibody (YA7986)(PBS only) glycogen; glycogen phosphorylase; glycogen storage disease type V; glycogen storage disease type V); McArdle syndrome; muscle; muscle (McArdle syndrome; myophosphorylase; phosphorylase	IHC-P	Human, Rat, Mouse
	PYGM Antibody (YA7986) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYGM.

HY-P80927

	VCAM1 Antibody (YA017) 2 Publications Verification VCAM1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD antigen CD106	WB, IHC-P, IP	Human, Mouse, Rat
	VCAM1 Antibody (YA017) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VCAM1.

HY-P85406

	VCAM1 Antibody (YA5098) VCAM1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD antigen CD106	WB, IHC-P, ICC/IF, IP, FC, IF-Tissue	Human, Mouse, Rat
	VCAM1 Antibody (YA5098) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to VCAM1.

HY-P81531

	VISTA Antibody (YA1276) VSIR; PP2135, UNQ730/PRO1412; C10orf54, SISP1; VISTA; V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; Stress-induced secreted protein-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor	IHC-P	Human
	VISTA Antibody (YA1276) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VISTA.

HY-P84641A

	Apoa5 Antibody (YA4338)(PBS only) RAP3; APOAV; APOA-V	WB, ELISA	Human
	Apoa5 Antibody (YA4338) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Apoa5.

HY-P81846

	Peroxiredoxin 5 Antibody (YA1591) ACR1; AOEB166; B166; Peroxiredoxin V; Peroxiredoxin-5; PLP; PMP20; PRDX5; PRDX6; Prx-V; PRXV; SBBI10; Thioredoxin reductase	WB, IHC-P, IP	Human, Mouse, Rat
	Peroxiredoxin 5 Antibody (YA1591) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Peroxiredoxin 5.

HY-P80927A

	VCAM1 Antibody (YA017)(PBS only) VCAM1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD antigen CD106	WB, IHC-P, IP	Human, Mouse, Rat
	VCAM1 Antibody (YA017) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VCAM1.

HY-P81531A

	VISTA Antibody (YA1276)(PBS only) VSIR; PP2135, UNQ730/PRO1412; C10orf54, SISP1; VISTA; V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; Stress-induced secreted protein-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor	IHC-P	Human
	VISTA Antibody (YA1276) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VISTA.

HY-P82466

	ATP6V1A Antibody (YA2211) HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; IECEE3; ATP6V1A1	WB, IHC-P, IP	Human, Mouse, Rat
	ATP6V1A Antibody (YA2211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATP6V1A.

HY-P82084

	Annexin V Antibody (YA1829) PP4; ANX5; ENX2; RPRGL3.	WB, ICC/IF	Human, Mouse, Rat
	Annexin V Antibody (YA1829) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Annexin V.

HY-P82802

	Cathepsin L/V/K/H Antibody (YA2547) Cathepsin; CTSL; CTSV; CTSK; CTSH	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Cathepsin L/V/K/H Antibody (YA2547) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cathepsin L/V/K/H.

HY-P81846A

	Peroxiredoxin 5 Antibody (YA1591)(PBS only) ACR1; AOEB166; B166; Peroxiredoxin V; Peroxiredoxin-5; PLP; PMP20; PRDX5; PRDX6; Prx-V; PRXV; SBBI10; Thioredoxin reductase	WB, IHC-P, IP	Human, Mouse, Rat
	Peroxiredoxin 5 Antibody (YA1591) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Peroxiredoxin 5.

HY-P82466A

	ATP6V1A Antibody (YA2211)(PBS only) HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; IECEE3; ATP6V1A1	WB, IHC-P, IP	Human, Mouse, Rat
	ATP6V1A Antibody (YA2211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATP6V1A.

HY-P82657

	Vitronectin Antibody (YA2402) VTN; Vitronectin; VN; S-protein; Serum-spreading factor; V75	WB, IHC-F, IHC-P, ICC/IF	Human
	Vitronectin Antibody (YA2402) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitronectin.

HY-P89154

	ATP6V0D2 Antibody (YA8838) ATP6D2; VMA6	WB, IHC-P	Human, Mouse, Rat
	ATP6V0D2 Antibody (YA8838) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to ATP6V0D2.

HY-P84015

	MYL3 Antibody (YA3712) CMH8; VLC1; MLC1V; MLC1SB	WB, IHC-P, ELISA	Human
	MYL3 Antibody (YA3712) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MYL3.

HY-P88516

	ATP6V1C2 Antibody (YA8200) ATP6C2; VMA5	IHC-P	Human, Mouse, Rat
	ATP6V1C2 Antibody (YA8200) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATP6V1C2.

HY-P88620

	ATP6V1F Antibody (YA8304) ATP6S14; VATF; Vma7	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	ATP6V1F Antibody (YA8304) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to ATP6V1F.

HY-P82084A

	Annexin V Antibody (YA1829)(PBS only) PP4; ANX5; ENX2; RPRGL3.	WB, ICC/IF	Human, Mouse, Rat
	Annexin V Antibody (YA1829) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Annexin V.

HY-P87432A

	CD101 Antibody (YA7120)(PBS only) CD101, EWI101, IGSF2, V7, Immunoglobulin superfamily member 2, IgSF2, Cell surface glycoprotein V7, Glu-Trp-Ile EWI motif-containing protein 101, EWI-101	FC, ELISA	Human
	CD101 Antibody (YA7120) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD101.

HY-P82657A

	Vitronectin Antibody (YA2402)(PBS only) VTN; Vitronectin; VN; S-protein; Serum-spreading factor; V75	WB, IHC-F, IHC-P, ICC/IF	Human
	Vitronectin Antibody (YA2402) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitronectin.

HY-P84022

	Annexin V Antibody (YA3719) PP4; ANX5; ENX2; RPRGL3; HEL-S-7	WB, ICC/IF, FC, ELISA	Human, Mouse
	Annexin V Antibody (YA3719) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Annexin V.

HY-P86818

	COL5A1 Antibody (YA6511) Collagen alpha-1(V) chain COL5A1	WB, ICC/IF, FC, IP	Human
	COL5A1 Antibody (YA6511) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to COL5A1.

HY-P84015A

	MYL3 Antibody (YA3712)(PBS only) CMH8; VLC1; MLC1V; MLC1SB	WB, IHC-P, ELISA	Human
	MYL3 Antibody (YA3712) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MYL3.

HY-P88516A

	ATP6V1C2 Antibody (YA8200)(PBS only) ATP6C2; VMA5	IHC-P	Human, Mouse, Rat
	ATP6V1C2 Antibody (YA8200) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATP6V1C2.

HY-P88620A

	ATP6V1F Antibody (YA8304)(PBS only) ATP6S14; VATF; Vma7	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	ATP6V1F Antibody (YA8304) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to ATP6V1F.

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Cat. No.	Product Name		Classification

HY-162874

diABZI-V/C-DBCO		DBCO
diABZI-V/C-DBCO is a STING agonist with an EC₅₀ of 1.47 nM. diABZI-V/C-DBCO activates the STING pathway, induces the production of IFN-I, and stimulates the secretion of IFN-β. diABZI-V/C-DBCO serves as a substrate for cathepsin B, and releases active diABZI-amine via cathepsin B-mediated cleavage. In an orthotopic mouse model of breast cancer, diABZI-V/C-DBCO increases serum IFN-β levels and the frequency of granzyme B ⁺ CD8 ⁺ T cells. diABZI-V/C-DBCO is applicable to research related to triple-negative breast cancer .

HY-176786

MCB-36		Alkynes
MCB-36 is a VHL-recruiting pan-KRAS PROTAC degrader without affecting KRAS transcription. MCB-36 exhibits minimal effects on HRAS and NRAS protein levels. MCB-36 binds to the GDP-loaded state of G12D, G12C, G12V, and wild-type KRAS with high affinities K_d ≈ 1 pM). MCB-36 decreases p-ERK levels, leading to cell apoptosis. MCB-36 effectively suppress KRAS ^G12C inhibitor-resistant cancer cells and remodel the tumor immune microenvironment. MCB-36 can be used for the study of colorectal cancer and lung cancer (Pink: Target protein ligand; Blue: E3 ligand (HY-112078); Black: Linker (HY-W091879)) .

HY-19476

AG-7404		Alkynes
AG-7404 is an orally active, irreversible inhibitor of the picornavirus 3C protease. AG-7404 blocks the processing of viral polyproteins, thereby inhibiting viral replication. AG-7404 has synergistic antiviral activity with capsid inhibitors such as V-073 (HY-104074) or BTA798 (HY-106254) and is effective against V-073-resistant variants. AG-7404 is used in the study of enterovirus infections such as poliovirus .

HY-159652

KRAS inhibitor-31 1 Publications Verification		Alkynes
KRAS inhibitor-31 (compound 33) is a KRAS inhibitor, with K_D (SPR) values of 0.019 nM, 0.019 nM and 0.096 nM for KRas G12D, KRas G12C and KRas G12V, respectively .

HY-176785S

MCB-294		Alkynes
MCB-294 is a dual-state pan-KRAS inhibitor that selectively inhibits KRAS over NRAS and HRAS. MCB-294 capable of binding both the active (GTP-bound) and inactive (GDP-bound) forms of KRAS with K_ds of approximately 1 pM and 10 nM, respectively. MCB-294 broadly impairs the growth of hTERT-HPNE cells expressing G12D, G12C, G12V, G12S, G13D, and wild-type KRAS, with IC₅₀s of approximately 700 nM. MCB-294 induces irreversible apoptosis in KRAS-mutated tumors. MCB-294 effectively suppress KRAS ^G12C inhibitor-resistant cancer cells and remodel the tumor immune microenvironment. MCB-294 can be used for the study of pancreatic cancer, colorectal cancer and lung cancer .

HY-114507

Flumioxazin Sumisoya; V-53482		Alkynes
Flumioxazin (Sumisoya) is an herbicide for use in soybean and peanut. Flumioxazin inhibits the enzyme protoporphyrinogen oxidase . Flumioxazin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-179253

KRAS-IN-47		Alkynes
KRAS-IN-47 is a KRAS inhibitor with IC₅₀ < 50 nM against KRAS G12V. KRAS-IN-47 can be used for the study of cancers .

HY-159474

KRAS inhibitor-24		Azide
KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC₅₀ of < 100 nM for KRas G12V, KRas WT and KRas G12R .

HY-179300A

KRAS-IN-48		Alkynes
KRAS-IN-48 (Compound 1-01) is a KRAS mutant inhibitor, with K_d values of 2.58 nM and 5.49 μM for KRAS-G12D and KRAS-G12V, respectively. KRAS-IN-48 can be used in the research of cancer .

HY-159476

KRAS inhibitor-26		Azide
KRAS inhibitor-26 (compound 194a) is a potent KRAS G12V inhibitor (IC₅₀: ≤100 nM). KRAS inhibitor-26 can be used for cancer research .

HY-179167

K2V-9		Alkynes
K2V-9 is an AChE and MAO-B inhibitor with IC₅₀ values of 1.72 μM and 0.950 μM against AChE and MAO-B, respectively. K2V-9 inhibits amyloid β self-aggregation and reduces ROS. K2V-9 has neuroprotective effects .

HY-162446

pan-KRAS-IN-13		Alkynes
pan-KRAS-IN-13 (compound 2) is a potent inhibitor of KRAS, with IC₅₀s of 2.75 nM and 2.89 nM for G12D and G12V, respectively

HY-149880

c-Met-IN-18		Alkynes
c-Met-IN-18 is ATP competitive type-III c-MET inhibitor of WT and D1228V mutant c-MET. c-Met-IN-18 has inhibitory for WT/D1228V with an IC₅₀ value of 0.013/0.20 ^e.c-Met-IN-18 can be used for the research of c-MET driven cancers . c-Met-IN-18 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-159475

KRAS inhibitor-25		Azide
KRAS inhibitor-25 (compound 151a) is a pyridopyrimidine KRAS inhibitor, with an IC₅₀ of < 100 nM against KRas G12V, KRas WT and KRas G12R .

HY-159473

K-Ras-IN-3		Alkynes
K-Ras-IN-3 (compound 3) is a potent GDP-KRAS G12V inhibitor with an IC₅₀ value of 0.371 nM. K-Ras-IN-3 has the potential for the research of cancer .

HY-167690

MK-6186		Alkynes
MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor with sub-nanomolar activity against wild-type viruses and the two most common NNRTI-resistant RT mutants (K103N and Y181C). MK-6186 exhibits excellent antiviral activity against K103N and Y181C mutant viruses. When MK-6186 targets 12 common NNRTI-associated mutant viruses, only two relatively rare mutants (Y188L and V106I/Y188L) show high resistance, with FC values exceeding 100, while the FC values of the remaining viruses are all below 10. In addition, when MK-6186 faces 96 clinical virus isolates carrying NNRTI-resistant mutations, most (70%) viruses show more than 10-fold resistance to efavirenz (EFV), while only 29% of mutant viruses show more than 10-fold resistance to MK-6186 .

HY-179300

KRAS-IN-48 free base		Alkynes
KRAS-IN-48 free base (Compound 1-01) is a mutant KRAS inhibitor, with K_d values of 2.58 nM and 5.49 μM for KRAS G12D and KRAS G12V, respectively. KRAS-IN-48 free base affects pERK expression in cells harboring KRAS G12D and KRAS G12V mutations, with IC₅₀ values of 1.1 μM and 1.51 μM, respectively. KRAS-IN-48 free base can be used in the research of cancer .

Cat. No.	Product Name		Classification

HY-RS01225

ATP6V1B2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1B2 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1B2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS03483

CYP4V2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CYP4V2 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP4V2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS29446

ATP6V1A Monkey Pre-designed siRNA Set A		siRNAs
ATP6V1A Monkey Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1A gene (Monkey), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01217

ATP6V0A2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V0A2 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V0A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS26708

Ube2v1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ube2v1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ube2v1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15365

UBE2V2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
UBE2V2 Human Pre-designed siRNA Set A contains three designed siRNAs for UBE2V2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15364

UBE2V1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
UBE2V1 Human Pre-designed siRNA Set A contains three designed siRNAs for UBE2V1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS28489

Ube2v2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ube2v2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ube2v2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS21972

Ube2v2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ube2v2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ube2v2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS10356

PF4V1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PF4V1 Human Pre-designed siRNA Set A contains three designed siRNAs for PF4V1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-R01700A

hsa-miR-548v agomir		MicroRNAs miRNA agomirs
hsa-miR-548v agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RS18574

Atp6v1a Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Atp6v1a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atp6v1a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01223

ATP6V1A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1A Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01230

ATP6V1F Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1F Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1F gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01220

ATP6V0C Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V0C Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V0C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01228

ATP6V1D Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1D Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01219

ATP6V0B Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V0B Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V0B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01234

ATP6V1H Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1H Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1H gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01216

ATP6V0A1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V0A1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V0A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01218

ATP6V0A4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V0A4 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V0A4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01232

ATP6V1G2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1G2 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1G2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01233

ATP6V1G3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1G3 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1G3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01224

ATP6V1B1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1B1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01229

ATP6V1E1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1E1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1E1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01227

ATP6V1C2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1C2 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1C2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01226

ATP6V1C1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1C1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1C1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01231

ATP6V1G1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V1G1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1G1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01221

ATP6V0D1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V0D1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V0D1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01222

ATP6V0D2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP6V0D2 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V0D2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-174542

Human PRKCB mRNA		mRNA
Human PRKCB mRNA encodes the human protein kinase C beta (PRKCB) protein, a member of Protein kinase C (PKC) family. PRKCB has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption.

HY-RS21513

Cdh23 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Cdh23 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdh23 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-174597

Human IL7R mRNA		mRNA Interleukin & Receptors
Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.

HY-R01700

hsa-miR-548v mimic		MicroRNAs miRNA mimics
hsa-miR-548v mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI01700

hsa-miR-548v inhibitor		MicroRNAs miRNA inhibitors
hsa-miR-548v inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RS20204

Ube2v1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ube2v1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ube2v1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS25058

Atp6v1a Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Atp6v1a Rat Pre-designed siRNA Set A contains three designed siRNAs for Atp6v1a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS27747

Atp6v1f Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Atp6v1f Rat Pre-designed siRNA Set A contains three designed siRNAs for Atp6v1f gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS21230

Atp6v1f Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Atp6v1f Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atp6v1f gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RI01700A

hsa-miR-548v antagomir		MicroRNAs miRNA antagomirs
hsa-miR-548v antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-185274

3'-O-(2-Nitrobenzyl)-dTTP		Nucleotide Analogs Thymine Nucleotide
3'-O-(2-Nitrobenzyl)-dTTP acts as a reversible terminator for DNA chain elongation. 3'-O-(2-Nitrobenzyl)-dTTP interacts with 9°N polymerase (exo-) A485L/Y409V, gets recognized and incorporated into the elongating DNA chain, thereby temporarily terminating the polymerase reaction. 3'-O-(2-Nitrobenzyl)-dTTP carries a 3'-O-(2-nitrobenzyl) blocking group, which can be removed by laser irradiation to regenerate the free 3'-OH ⁻ group and restore polymerase activity. 3'-O-(2-Nitrobenzyl)-dTTP is applicable in DNA sequencing studies .

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