Selpercatinib-13C,d3
Selpercatinib-13C,d3 (LOXO-292-13C,d3) is 13C labeled Selpercatinib. Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C2813CH28D3N7O3
- Molecular Weight:529.61
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 2152628-33-4
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Molecular Weight 529.61
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Formel C2813CH28D3N7O3
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SMILES
N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(O[13C]([2H])([2H])[2H])N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1
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Synonyms
LOXO-292-13C,d3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Selpercatinib-13C,d3 Related Classifications
HY-114370S Related Classifications
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