KRAS inhibitor-24
Based on 1 Customer Validation
KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R.
For research use only. We do not sell to patients.
- Purity: 95.03%
- CAS No.: 3030576-47-4
- Formula: C33H39ClF2N6O3
- Molecular Weight:641.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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KRas G12V < 100 nM (IC50) |
K-Ras WT < 100 nM (IC50) |
KRas G12R < 100 nM (IC50) |
Chemical Information
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CAS No. 3030576-47-4
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Appearance Solid
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Molecular Weight 641.15
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Formula C33H39ClF2N6O3
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Color White to off-white
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SMILES
FC1=C(C2=CC(O)=CC(Cl)=C2CCCCC(NCC[C@@]3([H])CN4CCC3)=O)N=CC(C1=N5)=C4N=C5OC[C@@]67N(CCC7)C[C@@H](C6)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)