RET-IN-27
RET-IN-27 (compound 20p) is a potent inhibitor of RET, with IC50s of 3.6 nM, 0.1 nM, 2.1 nM, 0.3 nM for RETWT, RETV804L, RETV804M, RETM918T, respectively. RET-IN-27 plays an important role in cancer research.
For research use only. We do not sell to patients.
- Formula: C31H28N8O
- Molecular Weight:528.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 528.61
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Formula C31H28N8O
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SMILES
N#CC1=CC(CN2C3CN(C4=NC=C(C5=C6C=CC=NC6=CC(C7=CN(C)N=C7)=N5)C=C4)CC2C3)=CC=C1OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)