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Referencia número: HY-182451

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V11294

V11294 is a phosphodiesterase 4 (PDE4) inhibitor with a K_i value of 436 nM against human lung PDE4. V11294 exhibits anti-inflammation activity.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 162278-10-6
Fòrmula: C₂₃H₃₁N₅O₂
Peso molecular:409.52

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

V11294 Chemical Structure

No. CAS: 162278-10-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
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Actividad biológica

Descripciòn

V11294 is a phosphodiesterase 4 (PDE4) inhibitor with a K_i value of 436 nM against human lung PDE4. V11294 exhibits anti-inflammation activity^[1].

IC₅₀ & Target^[1]

hPDE4D

436 nM (Ki)

Ver todos los productos específicos de isoformas Phosphodiesterase (PDE) :

In Vitro

V11294 (Compound 34) selectively inhibits human lung hPDE4 with a K_i of 436 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 162278-10-6
Peso molecular 409.52
Fòrmula C₂₃H₃₁N₅O₂
SMILES

CCNC1=C2N=C(C(C)C)N=C2N(CC3=CC=C(C(OC4CCCC4)=C3)OC)C=N1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Kodimuthali A, et al. Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease. J Med Chem. 2008 Sep 25;51(18):5471-89. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
Referencias

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V11294

Ver todos los productos específicos de isoformas Phosphodiesterase (PDE)