VEGFR-2/BRAF-IN-1
VEGFR-2/BRAF-IN-1 (Compound 4b) is a dual VEGFR-2 and BRAF kinases inhibitor with IC50 values of 0.049, 0.063 and 0.005 µM against VEGFR-2, BRAFV600E and BRAFWT, respectively. VEGFR-2/BRAF-IN-1 induces apoptosis and arrests the cell cycle mainly in the G1/S phase.
For research use only. We do not sell to patients.
- Formula: C26H20Cl2F3N5O3S2
- Molecular Weight:642.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All VEGFR Isoforms
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Biological Activity
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BRAFWT 0.005 μM (IC50) |
VEGFR2 0.049 μM (IC50) |
BRafV600E 0.063 μM (IC50) |
Chemical Information
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Molecular Weight 642.50
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Formula C26H20Cl2F3N5O3S2
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SMILES
O=C(NNC(NC1=CC(C(F)(F)F)=C(C=C1)Cl)=O)CSC2=NC3=C(C4=C(S3)CCCC4)C(N2C5=CC=C(C=C5)Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VEGFR-2/BRAF-IN-1 Related Classifications
HY-146491 Related Classifications
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