UNC8969
UNC8969 (compound 43) is a MERTK/AXL dual inhibitor with IC50s of 1.1±0.8 nM for MERTK and 5.3 ± 2.7 nM for AXL. UNC8969 also exerts a T1/2 of 7.3 h with 5 mg/kg i.v. in mice.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 3036049-17-6
- 화학식: C29H41N7O3
- 분자량:535.68
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
UNC8969 (0-1000 nM, 2 h) inhibits pMERTK and pAXL dose dependently in NSCLC cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3036049-17-6
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분자량 535.68
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화학식 C29H41N7O3
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SMILES
O=C(C1=C2NC3=CC=C(C(OC/C=C\CNC(N=C1)=N2)=C3)C)N[C@@H]4CC[C@H](CC4)C(NCCN(CC)CC)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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