KRAS inhibitor-26
KRAS inhibitor-26 is a KRas protein inhibitor with activity against dysregulated and mutant KRASG12C proteins. KRAS inhibitor-26 modulates KRAS-mediated signaling pathways. KRAS inhibitor-26 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3030576-80-5
- Formula: C36H39F3N6O4
- Molecular Weight:676.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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KRas G12V ≤100 nM (IC50) |
KRAS inhibitor-26 (Compound 194a) potently inhibits KRASG12V (with an IC50 of ≤100 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3030576-80-5
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Molecular Weight 676.73
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Formula C36H39F3N6O4
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SMILES
FC1=C2C(C3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=N2)=CN=C1C6=C7C(C=CC(F)=C7CCCC(NCCC8([H])CN3CCOC8)=O)=CC(O)=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRAS inhibitor-26 Related Classifications
HY-159476 Related Classifications
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