EGFR/BRAF-IN-1
EGFR/BRAF-IN-1 (compound 21), a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potent EGFR/BRAF inhibitor with an IC50 of 45 nM for BRAFV600E. EGFR/BRAF-IN-1 inhibits cancer cell proliferation (GI50=35 nM). EGFR/BRAF-IN-1 shows good antioxidant activity.
For research use only. We do not sell to patients.
- CAS No.: 2906174-89-6
- Formula: C26H28ClN3O4
- Molecular Weight:481.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
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EGFR |
BRafV600E 45 nM (IC50) |
Chemical Information
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CAS No. 2906174-89-6
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Molecular Weight 481.97
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Formula C26H28ClN3O4
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SMILES
CCOCC1=C2C(N(CC(N2C3=CC=C(C=C31)Cl)=O)CCC4=CC=C(C=C4)N5CCOCC5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)