THRA Antibody
(Synonyms: EAR7, ERBA1, NR1A1, THRA1, THRA2, THRA, Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, c-erbA-1, c-erbA-alpha, EAR-7)THRA Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to THRA.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
THRA Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to THRA.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 55 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 54 kDa
Synthetic peptide corresponding to the N-term region of human THRA.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
THRA is a Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
THRA has 4 isoforms, P10827-1: amino acid length is 490, molecular weight is 54816 Da (predicted); P10827-2: amino acid length is 410, molecular weight is 46813 Da (predicted); P10827-3: amino acid length is 451, molecular weight is 50747 Da (predicted); P10827-4: amino acid length is 448, molecular weight is 50465 Da (predicted).THRA 存在 4 个异构体,P10827-1:氨基酸个数为 490 个,分子量为 54816 Da (预测);P10827-2:氨基酸个数为 410 个,分子量为 46813 Da (预测);P10827-3:氨基酸个数为 451 个,分子量为 50747 Da (预测);P10827-4:氨基酸个数为 448 个,分子量为 50465 Da (预测)。
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Subunit
Binds DNA as a dimer; homodimer and heterodimer with RXRB.
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SwissProt ID
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Synonyms
EAR7, ERBA1, NR1A1, THRA1, THRA2, THRA, Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, c-erbA-1, c-erbA-alpha, EAR-7
Documentation