Vitronectin Antibody (YA2402)(PBS only)

Cat. No.: HY-P82657A: Data Sheet User Guide for Antibodies
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Vitronectin Antibody (YA2402) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitronectin.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Vitronectin Antibody (YA2402) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Vitronectin.

Host

Rabbit

Molecular Weight

Predicted band size: 54 kDa;

Observed band size: 70 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P04004

Gene ID

7448 [NCBI]

Immunogen

A synthetic peptide of human Vitronectin

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IHC-F IHC-F: Immunohistochemistry-Frozen	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway; Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity

Subcellular Localization：Secreted, extracellular space; Parasitophorous vacuole

Expression：
Tissue_specificity:Expressed in the retina pigment epithelium (at protein level) (PubMed:25136834) . Expressed in plasma (at protein level) (PubMed:2448300) . Expressed in serum (at protein level) (PubMed:29567995)

Subunit：Exists in two forms: a single chain 75 kDa form (V75) and a clipped form composed of two chains (65 kDa and 10 kDa) (V65+V10) which are held together by a disulfide bond. Interacts with SERPINE1/PAI1, insulin and C1QBP

Research Field

Cardiovascular

Synonyms

VTN; Vitronectin; VN; S-protein; Serum-spreading factor; V75

Documentation

User Guide for Antibodies (1077 KB)