KRAS inhibitor-25
KRAS inhibitor-25 (compound 151a) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM against KRas G12V, KRas WT and KRas G12R.
For research use only. We do not sell to patients.
- CAS No.: 3030577-05-7
- Formula: C32H38ClF2N5O3
- Molecular Weight:614.13
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
KRas G12C < 100 nM (IC50) |
K-Ras WT < 100 nM (IC50) |
KRas G12R < 100 nM (IC50) |
Chemical Information
-
CAS No. 3030577-05-7
-
Molecular Weight 614.13
-
Formula C32H38ClF2N5O3
-
SMILES
FC(C(C1=C(CCCCCC2)C(Cl)=CC(O)=C1)=NC=C34)=C3N=C(OC[C@]56N(C[C@H](F)C6)CCC5)N=C4N7CC2(O)CCC7
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz