ML389
ML389 is a highly selective vasopressin 1a (V1a) receptor antagonist (IC50=40 nM). ML389 is promising for research of central nervous system disorders such as anxiety, depression, and post-traumatic stress disorder (PTSD).
For research use only. We do not sell to patients.
- CAS No.: 1622294-25-0
- Formula: C21H23Cl2N3O
- Molecular Weight:404.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All Vasopressin Receptor Isoforms
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Biological Activity
Description
IC50 & Target
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V1a Receptor |
Chemical Information
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CAS No. 1622294-25-0
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Molecular Weight 404.33
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Formula C21H23Cl2N3O
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SMILES
O=C(C1CCN(C2=NC=C(Cl)C=C2)CC1)N(C3=CC=C(Cl)C=C3)CC4CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Mittapalli G, et al. Optimization and characterization of an antagonist for vasopressin 1a (V1a) receptor. 2013 Dec 11 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ML389 Related Classifications
HY-124275 Related Classifications
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