CST905
CST905 is a potent PROTAC degrader of BRAF-V600E with a DC50 of 18 nM. CST905 is suitable for cancer research.
(Pink: BRAF-V600E ligand (HY-41747); Blue: VHL ligand (HY-125845); Black: linker (HY-78378)).
For research use only. We do not sell to patients.
- CAS No.: 3094183-98-6
- Formula: C51H58F2N10O7S2
- Molecular Weight:1025.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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BRafV600E 18 nM (DC50) |
Chemical Information
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CAS No. 3094183-98-6
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Molecular Weight 1025.20
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Formula C51H58F2N10O7S2
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SMILES
O=C([C@H]1N(C([C@@H](NC(CN2CCN(C3=CC=C(C4=CN=C(NC=C5C(C6=C(F)C=CC(NS(=O)(N(CC)C)=O)=C6F)=O)C5=C4)C=C3)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC7=CC=C(C8=C(C)N=CS8)C=C7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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