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Cat. No.: HY-41747

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BRAF ligand-1

BRAF ligand-1 is the ligand of BRAF. BRAF ligand-1 can be used to synthesize CST905 (HY-175435).

For research use only. We do not sell to patients.

CAS No.: 2413037-31-5
Formula: C₁₇H₁₅BrF₂N₄O₃S
Molecular Weight:473.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BRAF ligand-1 Chemical Structure

CAS No.: 2413037-31-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

BRAF ligand-1 is the ligand of BRAF. BRAF ligand-1 can be used to synthesize CST905 (HY-175435)^[1].

IC₅₀ & Target

BRAF-V600E

All Raf Isoforms :

Chemical Information

CAS No. 2413037-31-5
Molecular Weight 473.29
Formula C₁₇H₁₅BrF₂N₄O₃S
SMILES

O=C(C1=C(F)C(NS(=O)(N(CC)C)=O)=CC=C1F)C2=CNC3=C2C=C(Br)C=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Miller DSJ, et al. Encoding BRAF inhibitor functions in protein degraders. RSC Med Chem. 2022 May 5;13(6):731-736. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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