1. MAPK/ERK Pathway
  2. Raf

HG6-64-1 (Synonyms: HG-6-64-01; HG-6-64-1; HG 6-64-1)

Cat. No.: HY-12291 Purity: 99.05%
Data Sheet SDS Handling Instructions

HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor; more information can be found in Patent WO 2011090738.

For research use only. We do not sell to patients.
HG6-64-1 Chemical Structure

HG6-64-1 Chemical Structure

CAS No. : 1315329-43-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO $445 In-stock
5 mg $350 In-stock
10 mg $500 In-stock
50 mg $1500 In-stock
100 mg $2100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor; more information can be found in Patent WO 2011090738. IC50 value: Target: B-Raf Preparation of pyrazine and pyrrolo[2,3-b]pyridine derivatives as b-raf kinase inhibitors useful in the treatment of cancer and proliferative diseases By Gray, Nathanael S. From PCT Int. Appl. (2011), WO 2011090738 A2 20110728.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.7312 mL 8.6559 mL 17.3118 mL
5 mM 0.3462 mL 1.7312 mL 3.4624 mL
10 mM 0.1731 mL 0.8656 mL 1.7312 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

577.64

Formula

C₃₂H₃₄F₃N₅O₂

CAS No.

1315329-43-1

Storage

4°C, protect from light, stored under nitrogen

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
HG6-64-1
Cat. No.:
HY-12291
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