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FGFR-IN-14

FGFR-IN-14 (compound 10h) is a pan-FGFR inhibitor. FGFR-IN-14 inhibits FGFR1, FGFR2, FGFR3 and FGFR2 V564F gatekeeper mutant with IC50s of 46, 41, 99, and 62 nM, respectively. FGFR-IN-14 strongly suppresses NCI-H520 lung cancer cells, SNU-16 and KATO III gastric cancer cells proliferation with IC50s of 19, 59, and 73 nM, respectively.

For research use only. We do not sell to patients.

  • CAS No.: 3047446-75-0
  • Formula: C24H19F2N7O2
  • Molecular Weight:475.45
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FGFR-IN-14 Chemical Structure
    FGFR-IN-14 Chemical Structure
CAS No.: 3047446-75-0
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  • FGFR-IN-14 Chemical Structure
    FGFR-IN-14 Chemical Structure
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  • FGFR-IN-14