JAK2-IN-11
Based on 1 Customer Validation
JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with IC50 ≤10 nM against JH2 BIND WT/V617F. JAK2-IN-11 has antitumor activity.
For research use only. We do not sell to patients.
- Purity: 98.03%
- CAS No.: 3057053-17-2
- Formula: C31H28D3F3N8O4
- Molecular Weight:639.64
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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JAK2-WT ≤10 nM (IC50) |
JAK2-V617F ≤10 nM (IC50) |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 3057053-17-2
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Appearance Solid
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Molecular Weight 639.64
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Formula C31H28D3F3N8O4
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Color White to off-white
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SMILES
O=C1N([C@H]2C[C@@H](CC2)NC(OC)=O)C3=CC(NC4=NC5=C(C=CC=C5C(F)(F)F)C(C(N6CCC(CC6)C#N)=O)=C4)=NC=C3N1C([2H])([2H])[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JAK2-IN-11 Related Classifications
HY-169326S Related Classifications
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