HIV gp120 (318-327)
HIV gp120 (318-327) is a short sequence of the HIV-1 strain IIIB envelope peptide (rgpgrafvti) that corresponds to the conserved C-terminal region of the glycoprotein. HIV gp120 (318-327) is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIV gp120 (318-327) lacks the A2 anchor residues recognized by epitope-specific CTLs but has structural features that confer promiscuous A2 binding.
For research use only. We do not sell to patients.
- CAS No.: 147841-68-7
- Formula: C48H80N16O12
- Molecular Weight:1073.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 147841-68-7
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Molecular Weight 1073.25
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Formula C48H80N16O12
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Sequence
Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile
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Sequence Shortening
RGPGRAFVTI
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kmieciak D, et al. The effect of deletion of the V3 loop of gp120 on cytotoxic T cell responses and HIV gp120-mediated pathogenesis. J Immunol. 1998 Jun 1;160(11):5676-83. [Content Brief]
[2]. Gu L, et al. A recombinant adenovirus-based vector elicits a specific humoral immune response against the V3 loop of HIV-1 gp120 in mice through the "Antigen Capsid-Incorporation" strategy. Virol J. 2014 Jun 16;11:112. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)