Fetrastobart
Based on 1 Customer Validation
Fetrastobart (SGN-PDL1V Antibody; PF-08046054 Antibody) is a PD-L1 targeting antibody. Fetrastobart can be used for synthesis of ADC SGN-PDL1V (HY-171821).
For research use only. We do not sell to patients.
- Purity: 98.77%
- CAS No.: 3028439-63-3
- Molecular Weight:144.90 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG1 kappa
Human
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa
ELISA, FACS, Functional assay
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Immobilized Human B7-H1/PD-L1/CD274, Fc Tag can bind SGN-PDL1V Antibody. The EC50 for this effect is 13.71 ng/mL. -
Flow cytometric analysis of 1X106 Jurkat cells with Fetrastobart (HY-P991506, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/50 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS No. 3028439-63-3
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Appearance Liquid
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Molecular Weight 144.90 kDa
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Color Colorless to light yellow
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SMILES
[Fetrastobart]
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Synonyms
SGN-PDL1V Antibody; PF-08046054 Antibody
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)