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  3. N-Acetyltyramine

N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells.

For research use only. We do not sell to patients.

N-Acetyltyramine Chemical Structure

N-Acetyltyramine Chemical Structure

CAS No. : 1202-66-0

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 72 In-stock
Solution
10 mM * 1 mL in DMSO USD 72 In-stock
Solid
5 mg USD 65 In-stock
10 mg USD 100 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells[1][2].

In Vitro

N-Acetyltyramine enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 µg/ml for doxorubicin alone[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

179.22

Formula

C10H13NO2

CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

OC1=CC=C(C=C1)CCNC(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (557.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5797 mL 27.8987 mL 55.7973 mL
5 mM 1.1159 mL 5.5797 mL 11.1595 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.5797 mL 27.8987 mL 55.7973 mL 139.4934 mL
5 mM 1.1159 mL 5.5797 mL 11.1595 mL 27.8987 mL
10 mM 0.5580 mL 2.7899 mL 5.5797 mL 13.9493 mL
15 mM 0.3720 mL 1.8599 mL 3.7198 mL 9.2996 mL
20 mM 0.2790 mL 1.3949 mL 2.7899 mL 6.9747 mL
25 mM 0.2232 mL 1.1159 mL 2.2319 mL 5.5797 mL
30 mM 0.1860 mL 0.9300 mL 1.8599 mL 4.6498 mL
40 mM 0.1395 mL 0.6975 mL 1.3949 mL 3.4873 mL
50 mM 0.1116 mL 0.5580 mL 1.1159 mL 2.7899 mL
60 mM 0.0930 mL 0.4650 mL 0.9300 mL 2.3249 mL
80 mM 0.0697 mL 0.3487 mL 0.6975 mL 1.7437 mL
100 mM 0.0558 mL 0.2790 mL 0.5580 mL 1.3949 mL
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N-Acetyltyramine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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N-Acetyltyramine
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