1. Membrane Transporter/Ion Channel
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  3. Esomeprazole Magnesium trihydrate

Esomeprazole Magnesium trihydrate (Synonyms: (S)-Omeprazole magnesium trihydrate)

Cat. No.: HY-17022
Handling Instructions

Esomeprazole Magnesium trihydrate is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.

For research use only. We do not sell to patients.

Esomeprazole Magnesium trihydrate Chemical Structure

Esomeprazole Magnesium trihydrate Chemical Structure

CAS No. : 217087-09-7

Size Price Stock Quantity
50 mg USD 156 In-stock
Estimated Time of Arrival: December 31
100 mg USD 264 In-stock
Estimated Time of Arrival: December 31
200 mg USD 360 In-stock
Estimated Time of Arrival: December 31
500 mg USD 798 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Other Forms of Esomeprazole Magnesium trihydrate:

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Description

Esomeprazole Magnesium trihydrate is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells. IC50 value: Target: proton pump Esomeprazole sodium (Nexium) is the S-isomer of omeprazole and acts as a proton pump inhibitor and gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis. Esomeprazole 0.4 and 0.8 mg/mL as the sodium salt in the infusion solutions tested is chemically and physically stable for at least 2 days at room temperature and 5 days under refrigeration.

Clinical Trial
Storage

4°C, protect from light

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (65.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3035 mL 6.5175 mL 13.0349 mL
5 mM 0.2607 mL 1.3035 mL 2.6070 mL
10 mM 0.1303 mL 0.6517 mL 1.3035 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5 mg/mL (6.52 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5 mg/mL (6.52 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 5 mg/mL (6.52 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

767.17

Formula

C₃₄H₄₂MgN₆O₉S₂

CAS No.

217087-09-7

SMILES

[H]O[H].[H]O[H].[H]O[H].O=S(CC1=NC=C(C)C(OC)=C1C)C2=NC(C=CC(OC)=C3)=C3[N-]2.O=S(CC4=NC=C(C)C(OC)=C4C)C5=NC(C=CC(OC)=C6)=C6[N-]5.[Mg+2]

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Esomeprazole Magnesium trihydrate
Cat. No.:
HY-17022
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Esomeprazole Magnesium trihydrate

Cat. No.: HY-17022