1. MAPK/ERK Pathway
  2. Raf
  3. PLX7922

PLX7922 

Cat. No.: HY-107415
Handling Instructions

PLX7922, a RAF inhibitor, can bind with BRAFV600E. PLX7922 inhibits pERK in BRAFV600E cell lines, and activates pERK in mutant NRAS cell lines.

For research use only. We do not sell to patients.

PLX7922 Chemical Structure

PLX7922 Chemical Structure

CAS No. : 1638772-61-8

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Description

PLX7922, a RAF inhibitor, can bind with BRAFV600E. PLX7922 inhibits pERK in BRAFV600E cell lines, and activates pERK in mutant NRAS cell lines[1].

IC50 & Target

RAF[1]

In Vitro

PLX7922 (1-1000 nM) inhibits pERK in BRAFV600E cell lines, activates pERK in mutant NRAS cell lines (B9 and IPC-298)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

464.58

Formula

C₂₀H₂₅FN₆O₂S₂

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
PLX7922
Cat. No.:
HY-107415
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