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Conivaptan hydrochloride (Standard)

(Synonyms: YM 087 (Standard))

Conivaptan hydrochloride (Standard) (YM 087 (Standard)) is the analytical standard of Conivaptan hydrochloride (HY-18347A). This product is intended for research and analytical applications. Conivaptan hydrochloride is an orally active dual vasopressin V1a/V2 receptor antagonist with Ki values of 0.48 nM and 3.04 nM for vasopressin V1a receptor and V2 receptor, respectively. Conivaptan hydrochloride competitively and reversibly blocks vasopressin-mediated antidiuresis, vasoconstriction, and cellular hypertrophy, while inhibiting CYP3A4. Conivaptan hydrochloride inhibits vasopressin-induced intracellular calcium, cAMP, and mitogen-activated kinase activation in vascular smooth muscle cells and cardiomyocytes. Conivaptan hydrochloride induces water diuresis while improving hemodynamics in heart failure models, reducing left ventricular end-diastolic pressure, vascular resistance, and organ weight. Conivaptan hydrochloride is used for research on hyponatremia and congestive heart failure.

For research use only. We do not sell to patients.

  • Purity: 98%
  • CAS No.: 168626-94-6
  • Formula: C32H27ClN4O2
  • Molecular Weight:535.04
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Conivaptan hydrochloride (Standard) Chemical Structure
    Conivaptan hydrochloride (Standard) Chemical Structure
CAS No.: 168626-94-6
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Conivaptan hydrochloride (Standard) Chemical Structure
    Conivaptan hydrochloride (Standard) Chemical Structure
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  • Conivaptan hydrochloride (Standard)