1. GPCR/G Protein
  2. Vasopressin Receptor

Balovaptan (Synonyms: RG7314; RO5028442)

Cat. No.: HY-109024
Handling Instructions

Balovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism.

For research use only. We do not sell to patients.

Balovaptan Chemical Structure

Balovaptan Chemical Structure

CAS No. : 1228088-30-9

Size Stock
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Balovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism.

IC50 & Target

Ki: 1 nM (hV1a), 39 nM (mV1a)[1]

In Vitro

Balovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for hV1a and mhV1a, and is used for the research of autism. Balovaptan shows >30000-fold selectivity for hV1a over hV2 receptors, 9891-fold selectivity over hOTR (human oxytocin receptor)[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4396 mL 12.1978 mL 24.3956 mL
5 mM 0.4879 mL 2.4396 mL 4.8791 mL
10 mM 0.2440 mL 1.2198 mL 2.4396 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

409.91

Formula

C₂₂H₂₄ClN₅O

CAS No.

1228088-30-9

SMILES

CN1CC2=NN=C([[email protected]]3CC[[email protected]](OC4=NC=CC=C4)CC3)[[email protected]]2[[email protected]]5=CC=C(Cl)C=C5C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Balovaptan
Cat. No.:
HY-109024
Quantity:

Balovaptan

Cat. No.: HY-109024