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Cat. No.: HY-186110

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PROTAC LRRK2 Degrader-5

PROTAC LRRK2 Degrader-5 Formula (V) is a LRRK2 PROTAC degrader. PROTAC LRRK2 Degrader-5 can be used for thet study of the diseases associated with LRRK2, such as Parkinson’s Disease (PD).

For research use only. We do not sell to patients.

CAS No.: 2839665-11-9
Formula: C₄₆H₅₇FN₁₀O₄
Molecular Weight:833.01

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PROTAC LRRK2 Degrader-5 Chemical Structure

CAS No.: 2839665-11-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

PROTAC LRRK2 Degrader-5 Formula (V) is a LRRK2 PROTAC degrader. PROTAC LRRK2 Degrader-5 can be used for thet study of the diseases associated with LRRK2, such as Parkinson’s Disease (PD)^[1].

All PROTACs Isoforms :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2839665-11-9
Molecular Weight 833.01
Formula C₄₆H₅₇FN₁₀O₄
SMILES

O=C1CCC(N2CC3=C(F)C(N4CCC(CN5CCN(CC6CCN(C7=CC(C8=NNC9=CC=C(OC%10(C)CC%10)C=C98)=NC=N7)CC6)C(C5)(C)C)CC4)=CC=C3C2=O)C(N1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Thomas Storz, et al. Synthesis of leucine-rich repeat kinase 2 modulators. WO2025123046A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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PROTAC LRRK2 Degrader-5

All PROTACs Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PROTAC LRRK2 Degrader-5 Related Classifications

HY-186110 Related Classifications