2. GPCR/G Protein
  3. Vasopressin Receptor
  4. V1b Receptor antagonist-1

V1b receptor antagonist-1 is a potent, selective and brain-penetrant vasopressin 1b (V1b) receptor antagonist. V1b receptor antagonist-1 exhibits anti-depressant activity. V1b receptor antagonist-1 can be used for the research of neurological disease, such as depression.

For research use only. We do not sell to patients.

V1b Receptor antagonist-1

V1b Receptor antagonist-1 Chemical Structure

CAS No. : 1056550-56-1

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V1b Receptor antagonist-1 Related Antibodies

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Description

V1b receptor antagonist-1 is a potent, selective and brain-penetrant vasopressin 1b (V1b) receptor antagonist. V1b receptor antagonist-1 exhibits anti-depressant activity. V1b receptor antagonist-1 can be used for the research of neurological disease, such as depression[1].

IC50 & Target[1]

V1b Receptor 

 

In Vivo

V1b receptor antagonist-1 (Compound 9c) (0.3-3 mg/kg, i.p.) shows anti-depressant activity in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Depressant rats models[1]
Dosage: 0.3, 1 and 3 mg/kg
Administration: Intraperitoneally injection
Result: Increased latency to immobility in the forced swimming test.
Molecular Weight

660.74

Formula

C36H32N6O5S
CAS No.
SMILES

N#CC1=CC=C2C(C(C3=CC(OC)=CC=C3OCC)(N4CCN(CC4)C5=CC=NC=C5)C(N2S(=O)(C6=CC=CC7=CC=CN=C76)=O)=O)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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V1b Receptor antagonist-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

V1b Receptor antagonist-11056550-56-1Vasopressin Receptorvasopressin 1banti-depressantdepressionratInhibitorinhibitorinhibit

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