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Cat. No.: HY-125714

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Isoapoptolidin

Isoapoptolidin is a mitochondrial F0F1-ATPase inhibitor (K_i>100 μM, selective for mitochondrial complex V). Isoapoptolidin is promising for research of mitochondrial energy metabolism-related diseases (e.g., cancer, neurodegeneration).

For research use only. We do not sell to patients.

CAS No.: 476647-30-0
Formula: C₅₈H₉₆O₂₁
Molecular Weight:1129.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Isoapoptolidin Chemical Structure

CAS No.: 476647-30-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 476647-30-0
Molecular Weight 1129.37
Formula C₅₈H₉₆O₂₁
SMILES

C/C1=C\C(C)=C\C(C)=C\[C@@H](C)[C@H](O[C@@H]2O[C@@H](C)[C@H](OC)[C@@H](O)[C@@H]2O)/C=C/C(C)=C/CC[C@H](O)[C@@H](OC)C[C@H](O)[C@H]([C@@]3(O)[C@H](C)[C@@H](O)[C@@H](C)[C@](C[C@@H](O[C@H]4C[C@](C)(O)[C@@H](O[C@@H]5O[C@H](C)[C@@H](O)[C@H](OC)C5)[C@H](C)O4)COC)([H])O3)OC1=O
Structure Classification
- Others
Initial Source
- Microorganisms
Nocardiopsis sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pennington JD, et al. Toward a stable apoptolidin derivative: identification of isoapoptolidin and selective deglycosylation of apoptolidin. Org Lett. 2002 Oct 31;4(22):3823-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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