Multi-target kinase-IN-8
Multi-target kinase-IN-8 (3d) is an anti-cancer agent. Multi-target kinase-IN-8 exhibits inhibitory activity against various protein kinases (B-Raf V600E (IC50 = 0.078 µg/mL), c-Met (IC50 = 0.405 µg/mL), Pim-1 (IC50 = 1.053 µg/mL), EGFR WT (IC50 = 0.177 µg/mL), VEGFR-2 (IC50 = 0.275 µg/mL)). Multi-target kinase-IN-8 can induce cell cycle arrest and promote early and late apoptosis. Multi-target kinase-IN-8 is commonly used in cancer research.
For research use only. We do not sell to patients.
- Formula: C27H20N6O
- Molecular Weight:444.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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VEGFR-2 0.275 μg/mL (IC50) |
BRafV600E 0.078 μg/mL (IC50) |
c-Met 0.405 μg/mL (IC50) |
EGFR (WT) 0.177 μg/mL (IC50) |
PIM1 1.053 μg/mL (IC50) |
Chemical Information
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Molecular Weight 444.49
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Formula C27H20N6O
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SMILES
N1(C2=CC=CC=C2)N=C(C3=CC4=CC=CC=C4O3)C(C5CC(C6=NC7=CC=CC=C7N6)=NN5)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Multi-target kinase-IN-8 Related Classifications
HY-179098 Related Classifications
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