Multi-target kinase-IN-8
Multi-target kinase-IN-8 (3d) is an anti-cancer agent. Multi-target kinase-IN-8 exhibits inhibitory activity against various protein kinases (B-Raf V600E (IC50 = 0.078 µg/mL), c-Met (IC50 = 0.405 µg/mL), Pim-1 (IC50 = 1.053 µg/mL), EGFR WT (IC50 = 0.177 µg/mL), VEGFR-2 (IC50 = 0.275 µg/mL)). Multi-target kinase-IN-8 can induce cell cycle arrest and promote early and late apoptosis. Multi-target kinase-IN-8 is commonly used in cancer research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C27H20N6O
- 分子量:444.49
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
VEGFR-2 0.275 μg/mL (IC50) |
BRafV600E 0.078 μg/mL (IC50) |
c-Met 0.405 μg/mL (IC50) |
EGFR (WT) 0.177 μg/mL (IC50) |
PIM1 1.053 μg/mL (IC50) |
化学情報
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分子量 444.49
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分子式 C27H20N6O
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SMILES
N1(C2=CC=CC=C2)N=C(C3=CC4=CC=CC=C4O3)C(C5CC(C6=NC7=CC=CC=C7N6)=NN5)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Multi-target kinase-IN-8 関連分類
HY-179098 関連分類
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