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Bivatuzumab

(Synonyms: BIWA 4; Anti-CD44 Recombinant Antibody)
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Bivatuzumab (BIWA 4) is a humanized monoclonal antibody targeting CD44v6. Bivatuzumab binds the v6 variant exon of CD44 with a Kd of 3.4 nM, undergoes internalization after binding, and achieves tumor localization. Bivatuzumab is inactive in antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity. Bivatuzumab can serve as the antibody component for synthesizing antibody-drug conjugates (ADCs), such as Bivatuzumab mertansine (BIWI 1). Bivatuzumab can be used for research on head and neck squamous cell carcinoma or esophageal squamous cell carcinoma.

For research use only. We do not sell to patients.

  • Purity : 99.82%
  • CAS No.: 214559-60-1
  • Molecular Weight:143.22 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Bivatuzumab
  • Experimental Validation Results for Bivatuzumab
  • Bivatuzumab Chemical Structure
    Bivatuzumab Chemical Structure
CAS No.: 214559-60-1
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Bivatuzumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow Cytometry analysis of A431 cells labelling CD44 (red) with Bivatuzumab (anti-CD44) (HY-P99281). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/200 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.

  • Bivatuzumab Chemical Structure
    1/16
  • Bivatuzumab
  • Flow Cytometry analysis of A431 cells labelling CD44 (red) with Bivatuzumab (anti-CD44) (HY-P99281). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/200 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.