ABCB1/ABCG2-IN-1
ABCB1/ABCG2-IN-1 (Compound (S,Z)-4b) is an inhibitor of ABCB1 and ABCB2 transporters. ABCB1/ABCG2-IN-1 shows moderate activity in SW620M, -V, and –Mito variants (IC50 ≈ 50 μM). ABCB1/ABCG2-IN-1 affects methotrexate resistance in vitro. ABCB1/ABCG2-IN-1 can be studied in anticancer research.
For research use only. We do not sell to patients.
- Formula: C24H22FeN2O2
- Molecular Weight:426.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 426.29
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Formula C24H22FeN2O2
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SMILES
O=C([C@@]1(CCCN1C/2=O)[H])NC2=C/C3=C(c4cccc4)C=CC=C3.[][Fe][].c5cccc5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)