Concanamycin F
Concanamycin F has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nM), which is an important tool for biochemical research.
For research use only. We do not sell to patients.
- CAS No.: 144539-92-4
- Formula: C39H64O10
- Molecular Weight:692.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 144539-92-4
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Molecular Weight 692.92
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Formula C39H64O10
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SMILES
O=C1O[C@H]([C@@H](C)[C@@H](O)[C@@H]([C@@]2(O)C[C@@H](O)[C@H](C)[C@@H](/C=C/C)O2)C)[C@@H](OC)/C=C/C=C(C)/C[C@@H](C)[C@H](O)[C@H](CC)[C@H](O)[C@H](C)/C=C(C)/C=C1\OC
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Structure Classification
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Initial Source
Streptomyces sp. A1509
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. I Paterson I, et al. Total Synthesis of (+)-Concanamycin F We thank the EPSRC (GR/K54052), Knoll Pharmaceuticals (CASE Studentship to V.A.D.), the Cambridge Commonwealth Trust (M.D.M.), and Merck for support, and Dr R. Norrie (Knoll Pharmaceuticals) for helpful discussions. We also thank Prof. A. Zeeck (Göttingen) for kindly providing copies of (1)H NMR spectra of concanamycin F (concanolide A). Angew Chem Int Ed Engl. 2000 Apr;39(7):1308-1312. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)