2. MAPK/ERK Pathway
  3. Raf
  4. Anticancer agent 124

Anticancer agent 124 is an orally active, highly selective and potent pan RAF inhibitor. Anticancer agent 124 inhibits MAPK signalling in BRAF V600E, NRAS and KRAS mutant tumor cells.

For research use only. We do not sell to patients.

Anticancer agent 124 Chemical Structure

Anticancer agent 124 Chemical Structure

CAS No. : 1884226-20-3

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Anticancer agent 124 Related Antibodies

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Description

Anticancer agent 124 is an orally active, highly selective and potent pan RAF inhibitor. Anticancer agent 124 inhibits MAPK signalling in BRAF V600E, NRAS and KRAS mutant tumor cells[1].

Molecular Weight

472.92

Formula

C26H21ClN4O3
CAS No.
SMILES

O=C1NC2=C(C(OC3=CC=C4C(CC(C5=NC=C(C6=CC=CC=C6Cl)N5)CO4)=C3)=CC=N2)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O : < 0.1 mg/mL (insoluble)

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Anticancer agent 124 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 1241884226-20-3Anticancer agent124Anticancer agent-124RafRaf kinasesBRAF V600E mutantRAF InhibitorREDX05358NRASKRASInhibitorinhibitorinhibit

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