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FUBP1 Antibody (YA1119)

(Synonyms: DNA helicase V; FBP; FUBP; Fubp1; Fubp4; FUSE-binding protein 1; HDH V)

FUBP1 Antibody (YA1119) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FUBP1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.217.

  • Conjugation:
    Non-conjugated
  • FUBP1 Antibody (YA1119) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:1000-1:5000

Product Details

Description

FUBP1 Antibody (YA1119) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FUBP1.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 74 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 68 kDa
Species Reactivity Database

Entrez Gene: 8880 Human

SwissProt: Q96AE4 Human

Immunogen

A synthesized peptide derived from human FUBP1

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.217.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    FUBP1 regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription

  • Subcellular Localization

    Nucleus

  • Isoforms & Post-Translational Modification

    Q96AE4 has 2 isomers: Q96AE4-1: 67560 Da (predicted); Q96AE4-2: 68605 Da (predicted).
    Ubiquitinated. This targets the protein for proteasome-mediated degradation

  • Subunit

    Found in a complex with PUF60 and far upstream element (FUSE) DNA segment. Interacts with PUF60 and JTV1

  • SwissProt ID

    Q96AE4

  • Gene ID
    8880 [NCBI]
  • Synonyms

    DNA helicase V; FBP; FUBP; Fubp1; Fubp4; FUSE-binding protein 1; HDH V

  • Research Field

    Epigenetics and Nuclear Signaling

FUBP1 Antibody (YA1119) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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