RET-IN-14
RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research
For research use only. We do not sell to patients.
- CAS No.: 2755843-62-8
- Formula: C24H23FN8O4
- Molecular Weight:506.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2755843-62-8
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Molecular Weight 506.49
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Formula C24H23FN8O4
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SMILES
NC1=C(C2=CC=C(C=C2)NC(OC)=O)C3=NC4=C(C(NC[C@@H](OC5=NC=C(F)C=C5CN3)C)=O)C=NN14
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)