pan-KRAS-IN-6
pan-KRAS-IN-6 (compound 12) is a potent pan KRAS inhibitor with IC50 values of 9.79 nM (Kras G12D) and 6.03 nM (Kras G12V).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 3033565-36-2
- Formule: C29H30ClF3N6O3S
- Masse moléculaire:635.10
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
KRas G12D 9.79 nM (IC50) |
KRas G12V 6.03 nM (IC50) |
In Vitro
pan-KRAS-IN-6 (20 nM; 72 h) has a good inhibitory effect on the growth of ASPC-1 cells (IC50=8.8 μm)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:AsPC-1 and SW480 cell lines
-
Concentration:20 nM
-
Incubation Time:72 h
-
Result:Inhibited the growth of AsPC-1 cell lines
Chemical Information
-
CAS No. 3033565-36-2
-
Masse moléculaire 635.10
-
Formule C29H30ClF3N6O3S
-
SMILES
FC1=C(C2=C(N=C(N)S3)C3=C(F)C=C2)C(Cl)=CC4=C(N5CC(C)(O)COCC5)N=C(OC[C@@]6(CCC7)N7C[C@H](F)C6)N=C14
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
pan-KRAS-IN-6 Related Classifications
HY-162439 Related Classifications
Powered by Bioz