pan-KRAS-IN-6
pan-KRAS-IN-6 (compound 12) is a potent pan KRAS inhibitor with IC50 values of 9.79 nM (Kras G12D) and 6.03 nM (Kras G12V).
For research use only. We do not sell to patients.
- CAS No.: 3033565-36-2
- Formula: C29H30ClF3N6O3S
- Molecular Weight:635.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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KRas G12D 9.79 nM (IC50) |
KRas G12V 6.03 nM (IC50) |
pan-KRAS-IN-6 (20 nM; 72 h) has a good inhibitory effect on the growth of ASPC-1 cells (IC50=8.8 μm)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:AsPC-1 and SW480 cell lines
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Concentration:20 nM
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Incubation Time:72 h
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Result:Inhibited the growth of AsPC-1 cell lines
Chemical Information
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CAS No. 3033565-36-2
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Molecular Weight 635.10
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Formula C29H30ClF3N6O3S
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SMILES
FC1=C(C2=C(N=C(N)S3)C3=C(F)C=C2)C(Cl)=CC4=C(N5CC(C)(O)COCC5)N=C(OC[C@@]6(CCC7)N7C[C@H](F)C6)N=C14
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
pan-KRAS-IN-6 Related Classifications
HY-162439 Related Classifications
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