pan-Raf/RTK inhibitor 1
Pan-Raf/RTK inhibitor 1 (compound I-16) is a potent pan-Raf inhibitor with IC50 values of 3.49 nM (BRafV600E), 8.86 nM (ARaf), 5.78 nM (BRafWT), and 1.65 nM (CRaf). Pan-Raf/RTK inhibitor 1 exhibits antiproliferative activities against various cancer cell lines and can be utilized in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1980821-53-1
- Formula: C29H28F3N7O3
- Molecular Weight:579.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1980821-53-1
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Molecular Weight 579.57
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Formula C29H28F3N7O3
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SMILES
O=C(C1=CC=C(C)C(NC(C2(CC2)C3=NC=NC4=C3NC=N4)=O)=C1)NC5=CC=C(CN6CCOCC6)C(C(F)(F)F)=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)