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Referencia número: HY-110314

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CYM50358 hydrochloride

Name: CYM50358 hydrochloride
Brand: MedChemExpress
SKU: HY-110314
Price: 300.00 USD
Availability: PreOrder

3 Cited Publications

Revisión del cliente

Based on 3 publication(s) in Google Scholar

CYM50358 hydrochloride (compound 4v) is a potent, selective sphingosine-1-phosphate 4 (S1P4) receptor antagonist. CYM50358 hydrochloride can be used in the study of influenza infection.

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No. CAS: 1781750-72-8
Fòrmula: C₂₀H₁₉Cl₃N₂O₂
Peso molecular:425.74

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

CYM50358 hydrochloride Chemical Structure

No. CAS: 1781750-72-8

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Descripciòn

CYM50358 hydrochloride (compound 4v) is a potent, selective sphingosine-1-phosphate 4 (S1P4) receptor antagonist. CYM50358 hydrochloride can be used in the study of influenza infection^[1].

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Chemical Information

No. CAS 1781750-72-8
Peso molecular 425.74
Fòrmula C₂₀H₁₉Cl₃N₂O₂
SMILES

O=C(C1=CC=C(O1)C2=C(C=CC(Cl)=C2)Cl)NC3=C(C=C(C=C3C)CN)C.Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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Cancer Commun (Lond)

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti-PD-1 immunotherapy efficacy in colorectal cancer liver metastasis. [Abstract]

2025 Jul 16. PMID: 40665874
Environ Pollut

Polycyclic aromatic hydrocarbon aggravates high-fat diet-induced metabolic dysfunction-associated steatotic liver disease through disturbing hepatocyte sphingolipid metabolism. [Abstract]

2025 Oct 15:383:126846. PMID: 40681076
Biomed Pharmacother

Apolipoprotein M bound sphingosine 1-phosphate suppresses NETosis through activating S1P1 and S1P4. [Abstract]

2023 Oct:166:115400. PMID: 37657263

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Guerrero M, et al. Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P4) receptor antagonists. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3632-6. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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3 Cited Publications

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CYM50358 hydrochloride

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Other In-stock Forms of CYM50358 hydrochloride

Publications Citing Use of MedChemExpress (MCE) CYM50358 hydrochloride

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Publications (3)

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