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  2. LPL Receptor
  3. CYM50358

CYM50358 

Cat. No.: HY-136462
Handling Instructions

CYM50358 is a potent and selective S1PR4 antagonist, with an IC50 of 25 nM. CYM50358 can be used for the research of influenza infection.

For research use only. We do not sell to patients.

CYM50358 Chemical Structure

CYM50358 Chemical Structure

CAS No. : 1314212-39-9

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Description

CYM50358 is a potent and selective S1PR4 antagonist, with an IC50 of 25 nM. CYM50358 can be used for the research of influenza infection[1][2].

IC50 & Target[1]

S1PR4

25 nM (IC50)

In Vitro

CYM50358 shows less potent inhibition of S1PR1 (IC50=6.4 μM)[1].
CYM50358 (10 μM) has no effect on the collagen-induced HSP27 phosphorylation, markedly reverses the suppressive effect of S1P on the collagen-induced phosphorylation of HSP27[2].

Molecular Weight

389.28

Formula

C₂₀H₁₈Cl₂N₂O₂

CAS No.

1314212-39-9

SMILES

O=C(C1=CC=C(C2=CC(Cl)=CC=C2Cl)O1)NC3=C(C)C=C(CN)C=C3C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

CYM50358CYM 50358CYM-50358LPL ReceptorLysophospholipid ReceptorS1PR4Inhibitorinhibitorinhibit

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