1. GPCR/G Protein
  2. LPL Receptor
  3. CYM50358


Cat. No.: HY-136462 Purity: 98.04%
COA Handling Instructions

CYM50358 is a potent and selective S1PR4 antagonist, with an IC50 of 25 nM. CYM50358 can be used for the research of influenza infection.

For research use only. We do not sell to patients.

CYM50358 Chemical Structure

CYM50358 Chemical Structure

CAS No. : 1314212-39-9

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 165 In-stock
10 mM * 1 mL in DMSO USD 165 In-stock
5 mg USD 150 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
50 mg USD 950 In-stock
100 mg USD 1550 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of CYM50358:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE CYM50358

View All LPL Receptor Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


CYM50358 is a potent and selective S1PR4 antagonist, with an IC50 of 25 nM. CYM50358 can be used for the research of influenza infection[1][2].

IC50 & Target[1]


25 nM (IC50)

In Vitro

CYM50358 shows less potent inhibition of S1PR1 (IC50=6.4 μM)[1].
CYM50358 (10 μM) has no effect on the collagen-induced HSP27 phosphorylation, markedly reverses the suppressive effect of S1P on the collagen-induced phosphorylation of HSP27[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight







Off-white to yellow




Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (321.11 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5688 mL 12.8442 mL 25.6885 mL
5 mM 0.5138 mL 2.5688 mL 5.1377 mL
10 mM 0.2569 mL 1.2844 mL 2.5688 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.08 mg/mL (5.34 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.08 mg/mL (5.34 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
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CYM50358 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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