PROTAC K-Ras Degrader-4

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PROTAC K-Ras Degrader-4 (Compound 4) is a PROTAC degrader for KRAS that degrades KRASG12D in GP5d and degrades KRASG12V in cell SW620 with DC50s of 1 nM and 13 nM. PROTAC K-Ras Degrader-4 inhibits MAPK signaling pathway.
(Pink: K-RAS ligand (HY-162960); Blue: Cereblon ligand (HY-W998248); Black: linker (HY-159790)).

For research use only. We do not sell to patients.

  • Purity: 99.01%
  • CAS No.: 2938169-99-2
  • Formula: C50H60N12O6S2
  • Molecular Weight:989.22
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
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100 mg

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